Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50012423
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557547(CHEMBL4792967)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557548(CHEMBL4761468)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557552(CHEMBL4747958)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557551(CHEMBL4745195)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557554(CHEMBL4756020)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557550(CHEMBL4790568)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557552(CHEMBL4747958)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557551(CHEMBL4745195)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557549(CHEMBL4800367)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557553(CHEMBL4744138)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557547(CHEMBL4792967)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557548(CHEMBL4761468)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557554(CHEMBL4756020)
Affinity DataIC50:  11nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557546(CHEMBL4747078)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant using biotinylated TK peptide as substrate measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557550(CHEMBL4790568)
Affinity DataIC50:  14nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557549(CHEMBL4800367)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557553(CHEMBL4744138)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50557546(CHEMBL4747078)
Affinity DataIC50:  51nMAssay Description:Inhibition of wild-type EGFR (unknown origin) using biotinylated TK peptide as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed