Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50012528
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120101BDBM50120101((2-Chloro-6-methyl-phenyl)-[8-(4-methyl-piperazin-...)
Affinity DataIC50: 1nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120116BDBM50120116(N*4*-(2-Chloro-6-methyl-phenyl)-N*7*-(2-dimethylam...)
Affinity DataIC50: 1.70nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120094BDBM50120094(N-(2-chloro-6-methylphenyl)-7,8-dimethoxyimidazo[1...)
Affinity DataIC50: 2nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120090BDBM50120090(N4-(2-chloro-6-methylphenyl)-N8,N8-diethylimidazo[...)
Affinity DataIC50: 2nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120087BDBM50120087(N-(2-chloro-6-methylphenyl)-8-(4-ethylpiperazin-1-...)
Affinity DataIC50: 2nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120125BDBM50120125((2-Chloro-6-methyl-phenyl)-[8-methoxy-7-(2-morphol...)
Affinity DataIC50: 2.40nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120097BDBM50120097((7,8-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...)
Affinity DataIC50: 2.40nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120128BDBM50120128(N*4*-(2-Chloro-6-methyl-phenyl)-N*8*-(3-morpholin-...)
Affinity DataIC50: 3nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120109BDBM50120109((2-Chloro-6-methyl-phenyl)-(8-methoxy-imidazo[1,5-...)
Affinity DataIC50: 3nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120093BDBM50120093((2-Chloro-6-methyl-phenyl)-(8-piperazin-1-yl-imida...)
Affinity DataIC50: 3nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120127BDBM50120127(N*4*-(2-Chloro-6-methyl-phenyl)-N*7*-(2-dimethylam...)
Affinity DataIC50: 3nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120130BDBM50120130(N-(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]q...)
Affinity DataIC50: 3nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120089BDBM50120089(N-(2-chloro-6-methylphenyl)-8-(3,5-dimethylpiperaz...)
Affinity DataIC50: 3nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120113BDBM50120113((2-chloro-6-methyl-phenyl)-(7,9-dioxa-2,5,10b-tria...)
Affinity DataIC50: 4nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120104BDBM50120104(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 4nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120111BDBM50120111(N-(2-chloro-6-methylphenyl)-8-morpholinoimidazo[1,...)
Affinity DataIC50: 4nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120115BDBM50120115(N4-(2-chloro-6-fluorophenyl)-N7-(2-(dimethylamino)...)
Affinity DataIC50: 5nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120108BDBM50120108(N*4*-(2-Chloro-6-methyl-phenyl)-N*8*,N*8*-dimethyl...)
Affinity DataIC50: 5nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120098BDBM50120098(N4-(2-chloro-6-methylphenyl)-8-methoxy-N7-(2-morph...)
Affinity DataIC50: 5.40nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120106BDBM50120106((2-Chloro-6-methyl-phenyl)-(7-morpholin-4-yl-imida...)
Affinity DataIC50: 6nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120112BDBM50120112(N*4*-(2-Chloro-6-methyl-phenyl)-N*8*-(2-dimethylam...)
Affinity DataIC50: 6nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120117BDBM50120117(N4-(2-chloro-6-methylphenyl)imidazo[1,5-a]quinoxal...)
Affinity DataIC50: 7nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120132BDBM50120132(N4-(2-chloro-6-methylphenyl)-N8-(2-morpholinoethyl...)
Affinity DataIC50: 7nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120123BDBM50120123(N-(2-chloro-6-methylphenyl)-7-(4-methylpiperazin-1...)
Affinity DataIC50: 8nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120122BDBM50120122((2-Chloro-6-methyl-phenyl)-(7-methoxy-imidazo[1,5-...)
Affinity DataIC50: 8.70nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120095BDBM50120095(4-(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]q...)
Affinity DataIC50: 9nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120091BDBM50120091(N*4*-(2-Chloro-6-methyl-phenyl)-N*7*-(3-dimethylam...)
Affinity DataIC50: 9nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120134BDBM50120134(N*4*-(2-Chloro-6-methyl-phenyl)-N*7*,N*7*-diethyl-...)
Affinity DataIC50: 9nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120126BDBM50120126((2-Chloro-6-methyl-phenyl)-[8-(4-methyl-[1,4]diaze...)
Affinity DataIC50: 9nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120099BDBM50120099(N-(2-chloro-6-methylphenyl)-9-methoxyimidazo[1,5-a...)
Affinity DataIC50: 9.40nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120124BDBM50120124(N*4*-(2-Chloro-6-methyl-phenyl)-N*8*-ethyl-imidazo...)
Affinity DataIC50: 10nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120114BDBM50120114((2-Chloro-6-methyl-phenyl)-(8,9-dihydro-7,10-dioxa...)
Affinity DataIC50: 10nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120110BDBM50120110(N4-(2-chloro-6-methylphenyl)-N7-(2-(dimethylamino)...)
Affinity DataIC50: 10nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120103BDBM50120103(N-(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]q...)
Affinity DataIC50: 11nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120105BDBM50120105((2-Chloro-6-methyl-phenyl)-(7-piperazin-1-yl-imida...)
Affinity DataIC50: 11nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120118BDBM50120118(N-(2-chloro-6-methylphenyl)-7-(3,5-dimethylpiperaz...)
Affinity DataIC50: 13nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120121BDBM50120121((7-Bromo-imidazo[1,5-a]quinoxalin-4-yl)-(2-chloro-...)
Affinity DataIC50: 14nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120131BDBM50120131(8-bromo-N-(2-chloro-6-methylphenyl)imidazo[1,5-a]q...)
Affinity DataIC50: 15nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120133BDBM50120133(N-(2-chloro-6-methylphenyl)-8-(3,5-dimethylpiperaz...)
Affinity DataIC50: 18nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120136BDBM50120136(N4-(2-chloro-6-methylphenyl)imidazo[1,5-a]quinoxal...)
Affinity DataIC50: 21nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120107BDBM50120107((2,6-Dichloro-phenyl)-(8-nitro-imidazo[1,5-a]quino...)
Affinity DataIC50: 24nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120100BDBM50120100(4-(2-Chloro-6-methyl-phenylamino)-imidazo[1,5-a]qu...)
Affinity DataIC50: 26nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120092BDBM50120092(N-(2-chloro-6-methylphenyl)-8-fluoroimidazo[1,5-a]...)
Affinity DataIC50: 26nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120135BDBM50120135(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 30nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120102BDBM50120102((2-Chloro-6-methyl-phenyl)-[7-methoxy-8-(2-morphol...)
Affinity DataIC50: 36nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120119BDBM50120119(N4-(2,6-dimethylphenyl)imidazo[1,5-a]quinoxaline-4...)
Affinity DataIC50: 70nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120120BDBM50120120(N-(2,6-dimethylphenyl)-9-nitroimidazo[1,5-a]quinox...)
Affinity DataIC50: 100nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120096BDBM50120096(4-(2-chloro-6-methylphenylamino)imidazo[1,5-a]quin...)
Affinity DataIC50: 100nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112918BDBM50112918(N-(2-bromophenyl)imidazo[1,5-a]quinoxalin-4-amine ...)
Affinity DataIC50: 170nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120088BDBM50120088(9-(benzyloxy)-N-(2-chloro-6-methylphenyl)imidazo[1...)
Affinity DataIC50: 240nMAssay Description:50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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