Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50013095
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126528BDBM50126528(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  0.0230nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126525BDBM50126525(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  0.0570nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126521BDBM50126521(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  0.0870nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126508BDBM50126508(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  0.240nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126520BDBM50126520(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  0.270nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126526BDBM50126526(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  0.320nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126500BDBM50126500(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  0.75nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126514BDBM50126514(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126523BDBM50126523(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126529BDBM50126529(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126532BDBM50126532(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126534BDBM50126534(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126505BDBM50126505(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  5.70nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126519BDBM50126519(2-[1-(4-Chloro-phenylsulfanylmethyl)-2-morpholin-4...)
Affinity DataKi:  7.70nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126513BDBM50126513(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126506BDBM50126506(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126510BDBM50126510(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126501BDBM50126501(2-[1-(3,4-Dichloro-phenylsulfanylmethyl)-2-oxo-2-p...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126503BDBM50126503(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  22nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126516BDBM50126516(2-[1-(4-Chloro-phenylsulfanylmethyl)-2-oxo-2-pyrro...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126511BDBM50126511(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126522BDBM50126522(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126512BDBM50126512(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  29nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126517BDBM50126517(2-[1-(4-Bromo-phenylsulfanylmethyl)-2-oxo-2-pyrrol...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126531BDBM50126531(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126535BDBM50126535(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126507BDBM50126507(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  36nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126515BDBM50126515(2-[1-(4-Bromo-phenylsulfanylmethyl)-2-morpholin-4-...)
Affinity DataKi:  39nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126518BDBM50126518(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  53nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126533BDBM50126533(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  53nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126527BDBM50126527(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  78nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126509BDBM50126509(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126502BDBM50126502(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  82nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126504BDBM50126504(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  83nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126524BDBM50126524(2-{5-[(6-Amino-2-methyl-pyridin-3-ylmethyl)-carbam...)
Affinity DataKi:  87nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126530BDBM50126530(2-{5-[(4-Amino-cyclohexylmethyl)-carbamoyl]-1,3-di...)
Affinity DataKi:  91nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed