Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50013729
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKi:  1.19E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKi:  2.54E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKi:  5.79E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKi:  9.94E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataIC50:  5.18E+3nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50223368(3beta-hydroxyandrost-5-en-17-one | CHEMBL90593 | D...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50362839(CHEMBL249447)
Affinity DataIC50:  3.77E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM60919((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[3-[(E)-2-(4-...)
Affinity DataIC50:  7.45E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKd:  3.64E+3nMAssay Description:Binding affinity to G6PD (unknown origin) assessed as equilibrium dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed