Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50013729
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  1.19E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  2.54E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKd:  3.64E+3nMAssay Description:Binding affinity to G6PD (unknown origin) assessed as equilibrium dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  5.79E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  9.94E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50223368(Prasterone | 3beta-hydroxyandrost-5-en-17-one | CH...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50362839(CHEMBL249447)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM60919(MLS001424114 | SMR000466371 | cid_5281718 | (2S,3R...)
Affinity DataIC50: 7.45E+4nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed