Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50015985
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591018BDBM50591018(CHEMBL5204203)
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591016BDBM50591016(CHEMBL5175156)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591017BDBM50591017(CHEMBL5206022)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591022BDBM50591022(CHEMBL5197367)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591035BDBM50591035(CHEMBL5187422)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of N-terminal His8-tagged/C-terminal FLAG-tagged full length human DNA polymerase theta ( 1 to 2590 residues) polymerase activity expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591030BDBM50591030(CHEMBL5174509)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591026BDBM50591026(CHEMBL5197173)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591015BDBM50591015(CHEMBL5170373)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591028BDBM50591028(CHEMBL5194637)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591027BDBM50591027(CHEMBL5197021)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591019BDBM50591019(CHEMBL5187337)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591024BDBM50591024(CHEMBL5188048)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591033BDBM50591033(CHEMBL5181369)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591029BDBM50591029(CHEMBL5174376)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591032BDBM50591032(CHEMBL5200250)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591021BDBM50591021(CHEMBL5174283)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591020BDBM50591020(CHEMBL5195161)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591023BDBM50591023(CHEMBL5194194)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591034BDBM50591034(CHEMBL5206029)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591031BDBM50591031(CHEMBL5202450)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591035BDBM50591035(CHEMBL5187422)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591002BDBM50591002(CHEMBL5195920)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human DNA polymerase theta using DNA 16/19 as substrate at 1 nM of enzyme concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591002BDBM50591002(CHEMBL5195920)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human DNA polymerase theta using DNA 16/19 as substrate at 0.5 nM of enzyme concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591002BDBM50591002(CHEMBL5195920)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human DNA polymerase theta using DNA 16/19 as substrate at 2 nM of enzyme concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591025BDBM50591025(CHEMBL5200171)
Affinity DataIC50: 9nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591002BDBM50591002(CHEMBL5195920)
Affinity DataIC50: 10nMAssay Description:Inhibition of human DNA polymerase theta using 5'-CACTGACTGTATGATG as primer and DNA 16/19 as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591002BDBM50591002(CHEMBL5195920)
Affinity DataIC50: 11nMAssay Description:Inhibition of human DNA polymerase theta using DNA 16/19 as substrate at 5 nM of enzyme concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591003BDBM50591003(CHEMBL5203967)
Affinity DataIC50: 14nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591014BDBM50591014(CHEMBL5178605)
Affinity DataIC50: 14nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591002BDBM50591002(CHEMBL5195920)
Affinity DataIC50: 17nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591012BDBM50591012(CHEMBL5185359)
Affinity DataIC50: 17nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591012BDBM50591012(CHEMBL5185359)
Affinity DataIC50: 19nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591006BDBM50591006(CHEMBL5178606)
Affinity DataIC50: 40nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591013BDBM50591013(CHEMBL5206197)
Affinity DataIC50: 42nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591008BDBM50591008(CHEMBL5208584)
Affinity DataIC50: 58nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591007BDBM50591007(CHEMBL5181730)
Affinity DataIC50: 65nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591005BDBM50591005(CHEMBL5200543)
Affinity DataIC50: 121nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590990BDBM50590990(CHEMBL5185248)
Affinity DataIC50: 170nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590997BDBM50590997(CHEMBL5175626)
Affinity DataIC50: 240nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590999BDBM50590999(CHEMBL5199017)
Affinity DataIC50: 520nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591000BDBM50591000(CHEMBL5170248)
Affinity DataIC50: 560nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590995BDBM50590995(CHEMBL5190448)
Affinity DataIC50: 710nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591035BDBM50591035(CHEMBL5187422)
Affinity DataIC50: 940nMAssay Description:Inhibition of DNA polymerase theta in LIG4 knock out HEK293T cells assessed as decrease in MMEJ-mediated DNA repair preincubated for 1 day followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590998BDBM50590998(CHEMBL5188740)
Affinity DataIC50: 950nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591011BDBM50591011(CHEMBL5205344)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591001BDBM50591001(CHEMBL5181359)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591009BDBM50591009(CHEMBL5190798)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591010BDBM50591010(CHEMBL5202303)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591004BDBM50591004(CHEMBL5195660)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590996BDBM50590996(CHEMBL5188985)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
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