Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50018675
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611061BDBM50611061(CHEMBL5291234)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to METTL3 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611058BDBM50611058(CHEMBL5279050)
Affinity DataIC50: 17nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as reduction in m6A methylation levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611061BDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611058BDBM50611058(CHEMBL5279050)
Affinity DataIC50: 280nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611052BDBM50611052(CHEMBL5270921)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611059BDBM50611059(CHEMBL5286034)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611060BDBM50611060(CHEMBL5288865)
Affinity DataIC50: 5.17E+4nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611055BDBM50611055(CHEMBL5282296)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611056BDBM50611056(CHEMBL5276433)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611057BDBM50611057(CHEMBL5286336)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611054BDBM50611054(CHEMBL5281978)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611053BDBM50611053(CHEMBL5281651)
Affinity DataIC50: 3.32E+5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14487BDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed