Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50019836
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234318BDBM50234318(CHEMBL4091294)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459995BDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50: 37nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-C(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623583BDBM50623583(CHEMBL5421134)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623583BDBM50623583(CHEMBL5421134)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623573BDBM50623573(CHEMBL5441138)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445250BDBM50445250(CHEMBL3102859)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623575BDBM50623575(CHEMBL5406308)
Affinity DataIC50: 62nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623567BDBM50623567(CHEMBL5434520)
Affinity DataIC50: 85nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623571BDBM50623571(CHEMBL5440418)
Affinity DataIC50: 98nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623578BDBM50623578(CHEMBL5399338)
Affinity DataIC50: 107nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623582BDBM50623582(CHEMBL5415489)
Affinity DataIC50: 116nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623572BDBM50623572(CHEMBL5431726)
Affinity DataIC50: 136nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623574BDBM50623574(CHEMBL5403765)
Affinity DataIC50: 143nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623576BDBM50623576(CHEMBL5409187)
Affinity DataIC50: 152nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623569BDBM50623569(CHEMBL5399686)
Affinity DataIC50: 162nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623570BDBM50623570(CHEMBL5409281)
Affinity DataIC50: 213nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623581BDBM50623581(CHEMBL2000568)
Affinity DataIC50: 216nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623586BDBM50623586(CHEMBL5412040)
Affinity DataIC50: 221nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623585BDBM50623585(CHEMBL5426252)
Affinity DataIC50: 225nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623577BDBM50623577(CHEMBL5412342)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623568BDBM50623568(CHEMBL5397227)
Affinity DataIC50: 265nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623584BDBM50623584(CHEMBL5083764)
Affinity DataIC50: 276nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623583BDBM50623583(CHEMBL5421134)
Affinity DataIC50: 428nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623580BDBM50623580(CHEMBL5075969)
Affinity DataIC50: 456nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623579BDBM50623579(CHEMBL5076124)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623583BDBM50623583(CHEMBL5421134)
Affinity DataIC50: 594nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623583BDBM50623583(CHEMBL5421134)
Affinity DataIC50: 711nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623583BDBM50623583(CHEMBL5421134)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin) preincubated for 10 mins followed by substrate addition measured for 60 to 120 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed