Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50020176
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  1.78nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  1.86nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210955((1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicycl...)
Affinity DataKi:  1.98nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210955((1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicycl...)
Affinity DataKi:  2.25nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  2.26nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  3.45nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210955((1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicycl...)
Affinity DataKi:  4.16nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210951((1R,2S,3R,5R)-methyl 3-(4-vinylphenyl)-8-aza-bicyc...)
Affinity DataKi:  4.67nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210952((1R,2S,3R,5R)-methyl 3-p-tolyl-8-aza-bicyclo[3.2.1...)
Affinity DataKi:  4.88nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  6.42nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210951((1R,2S,3R,5R)-methyl 3-(4-vinylphenyl)-8-aza-bicyc...)
Affinity DataKi:  9.04nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210951((1R,2S,3R,5R)-methyl 3-(4-vinylphenyl)-8-aza-bicyc...)
Affinity DataKi:  10.1nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210952((1R,2S,3R,5R)-methyl 3-p-tolyl-8-aza-bicyclo[3.2.1...)
Affinity DataKi:  11.5nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  42.8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210952((1R,2S,3R,5R)-methyl 3-p-tolyl-8-aza-bicyclo[3.2.1...)
Affinity DataKi:  136nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed