Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50021251
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16315BDBM16315(CP-744809 | CHEMBL240725 | 6-[(5-chloro-3-methyl-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009767BDBM50009767(2-(4-oxo-3-((6-(trifluoromethyl)benzo[d]thiazol-2-...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16469BDBM16469(Indoleacetic Acid Inhibitor 9 | 2-{3-[(4,5,7-trifl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16239BDBM16239(2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}ph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222613BDBM50222613(2-(2-((3-nitrobenzyl)carbamoyl)-4-cyano-5-fluoroph...)
Affinity DataIC50: 7nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222611BDBM50222611(2-(5-fluoro-2-(((4,5,7-trifluorobenzo[d]thiazol-2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067407BDBM50067407((3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[p...)
Affinity DataIC50: 15nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16457BDBM16457(CHEMBL240722 | 6-[(5-chloro-1-benzofuran-2-)sulfon...)
Affinity DataIC50: 25nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222614BDBM50222614(2-(5-fluoro-2-(((5-(trifluoromethyl)benzo[d]thiazo...)
Affinity DataIC50: 29nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16313BDBM16313(IDD594 | LdT | CHEMBL395347 | {2-[(4-bromo-2-fluor...)
Affinity DataIC50: 30nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222609BDBM50222609(2-(5-chloro-2-(((5-(trifluoromethyl)benzo[d]thiazo...)
Affinity DataIC50: 35nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16512BDBM16512((2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chrome...)
Affinity DataIC50: 35nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16496BDBM16496(CHEMBL10413 | FR 74366 | [3-(4-bromo-2-fluorobenzy...)
Affinity DataIC50: 44nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009777BDBM50009777(Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...)
Affinity DataIC50: 56.5nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038843BDBM50038843(2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spi...)
Affinity DataIC50: 73nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16631BDBM16631(6-[(5,7-dichloro-1-benzofuran-2-)sulfonyl]-2,3-dih...)
Affinity DataIC50: 87nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222612BDBM50222612(2-(2,6-dimethyl-4-(2-o-tolylacetamido)phenylsulfon...)
Affinity DataIC50: 108nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16456BDBM16456(CHEMBL241777 | Heterocyclic Sulfonylpyridazinone, ...)
Affinity DataIC50: 150nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222610BDBM50222610(2-(2-((4-bromo-2-fluorobenzyl)carbamoyl)phenoxy)ac...)
Affinity DataIC50: 176nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067397BDBM50067397((3S)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[p...)
Affinity DataIC50: 190nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16630BDBM16630(6-[(5-methoxy-1-benzofuran-2-)sulfonyl]-2,3-dihydr...)
Affinity DataIC50: 230nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089423BDBM50089423(6-fluoro-2',5'-dioxo-(2R,4'S)-spiro[3,4-dihydro-2H...)
Affinity DataIC50: 570nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16623BDBM16623(6-[(5-chloro-1H-indole-2-)sulfonyl]-2,3-dihydropyr...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16312BDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16426BDBM16426(CHEMBL240714 | Benzeneacetic acid | 2-(2-hydroxyph...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16429BDBM16429(CHEMBL240293 | EINECS 229-504-0 | 2-(2,6-dichlorop...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16433BDBM16433(CHEMBL14184 | Caproic acid | n-Caproic acid | Hexa...)
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Università

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16419BDBM16419(Phenylacetate, XIX | Benzeneacetic acid | phenylac...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)