Compile Data Set for Download or QSAR
Report error Found 77 Enz. Inhib. hit(s) with all data for entry = 50021727
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81783BDBM81783(CAS_82830-44-2 | (+/-)-1-(2,5-DIMETHOXY-4-IODOPHEN...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity to human [125I]DOI-labeled 5-HT2A receptor expressed in HEK293 cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644105BDBM50644105(CHEMBL5563360 | US20250236589, Compound I-1)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]DOI from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81783BDBM81783(CAS_82830-44-2 | (+/-)-1-(2,5-DIMETHOXY-4-IODOPHEN...)
Affinity DataKi:  0.480nMAssay Description:Binding affinity to human [125I]DOI-labeled 5-HT2C receptor expressed in HEK293 cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644105BDBM50644105(CHEMBL5563360 | US20250236589, Compound I-1)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]DOI from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377957BDBM50377957(CHEMBL1788118)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21359BDBM21359(5-HT | [3H]-5-HT)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]LSD from 5-HT7 receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644121BDBM50644121(CHEMBL5592769 | US20250236589, Compound I-11)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81783BDBM81783(CAS_82830-44-2 | (+/-)-1-(2,5-DIMETHOXY-4-IODOPHEN...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human [125I]DOI-labeled 5-HT2B receptor expressed in CHO cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644108BDBM50644108(CHEMBL5574455)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013515BDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2C receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644122BDBM50644122(CHEMBL5591197)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013515BDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644120BDBM50644120(CHEMBL5566821)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644120BDBM50644120(CHEMBL5566821)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to human [125I]LSD-labeled 5-HT2A receptor expressed in HEK293 cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644116BDBM50644116(CHEMBL5569144)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644114BDBM50644114(CHEMBL5573972 | US20250236589, Compound I-2)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644111BDBM50644111(CHEMBL5594012)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644128BDBM50644128(CHEMBL5589604 | US20250236589, Compound I-4)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644106BDBM50644106(CHEMBL5565116)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644107BDBM50644107(CHEMBL5572387)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644105BDBM50644105(CHEMBL5563360 | US20250236589, Compound I-1)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]DOI from human 5-HT2B receptor expressed in CHO cell membrane incubated for 90 mins by microbeta liquid scintillation counting me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644120BDBM50644120(CHEMBL5566821)
Affinity DataKi:  6.70nMAssay Description:Binding affinity to human [125I]LSD-labeled 5-HT2C receptor expressed in HEK293 cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644115BDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644128BDBM50644128(CHEMBL5589604 | US20250236589, Compound I-4)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644125BDBM50644125(CHEMBL5566894)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644108BDBM50644108(CHEMBL5574455)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644115BDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644126BDBM50644126(CHEMBL5571221 | US20250236589, Compound V-1)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013515BDBM50013515(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2B receptor expressed in human CHO-K1 cells incubated for 60 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644131BDBM50644131(CHEMBL5575032 | US20250236589, Compound VI-1)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644113BDBM50644113(CHEMBL5584114)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644114BDBM50644114(CHEMBL5573972 | US20250236589, Compound I-2)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644120BDBM50644120(CHEMBL5566821)
Affinity DataKi:  10nMAssay Description:Binding affinity to human [125I]LSD-labeled 5-HT2B receptor expressed in CHO cell membrane incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644116BDBM50644116(CHEMBL5569144)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644114BDBM50644114(CHEMBL5573972 | US20250236589, Compound I-2)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644110BDBM50644110(CHEMBL5572320)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644128BDBM50644128(CHEMBL5589604 | US20250236589, Compound I-4)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225285BDBM50225285(CHEBI:3757 | Catapres | Catapres-Tts-1 | Catapres-...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-rauwolscine from human recombinant adrenergic alpha-2B receptor expressed in human CHO-K1 cells incubated for 60 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644108BDBM50644108(CHEMBL5574455)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644120BDBM50644120(CHEMBL5566821)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644106BDBM50644106(CHEMBL5565116)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21359BDBM21359(5-HT | [3H]-5-HT)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]5-CT from 5-HT1B receptor (unknown origin) assessed as inhibition bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644107BDBM50644107(CHEMBL5572387)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644110BDBM50644110(CHEMBL5572320)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644107BDBM50644107(CHEMBL5572387)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644115BDBM50644115(CHEMBL5563542 | US20250236589, Compound I-3)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]LSD from human 5-HT2A receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644106BDBM50644106(CHEMBL5565116)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644113BDBM50644113(CHEMBL5584114)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644109BDBM50644109(CHEMBL5573377)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Cybin IRL

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644111BDBM50644111(CHEMBL5594012)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]LSD from human 5-HT2C receptor expressed in HEK293 cell membrane incubated for 90 mins by microbeta liquid scintillation counting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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