Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50022622
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd: <1nMAssay Description:Binding affinity to BRD9 (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd: <1nMAssay Description:Binding affinity to BRD7 (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  1nMAssay Description:Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183561(CHEMBL3824146)
Affinity DataIC50: 13nMAssay Description:Inhibition of amino terminal GST tagged BRD9 (aa 130-259 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 K9/14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 21nMAssay Description:Inhibition of amino terminal GST tagged BRD9 (aa 130-259 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 K9/14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50183561(CHEMBL3824146)
Affinity DataIC50: 42nMAssay Description:Inhibition of BRD7 (unknown origin) using histone H3 K9/14/18/23Ac (1-28) peptide as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 67nMAssay Description:Inhibition of amino terminal GST tagged BRD9 (aa 130-259 residues) (unknown origin) expressed in Escherichia coli using biotinylated histone H3 K9/14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 71nMAssay Description:Inhibition of BRD7 (unknown origin) using histone H3 K9/14/18/23Ac (1-28) peptide as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  100nMAssay Description:Binding affinity to TAF1 (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetPeregrin(Human)TBA
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  100nMAssay Description:Binding affinity to BRPF1B (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  100nMAssay Description:Binding affinity to FALZ (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 644nMAssay Description:Inhibition of BRD7 (unknown origin) using histone H3 K9/14/18/23Ac (1-28) peptide as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to BAZ2B (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetCREB-binding protein(Human)TBA
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to CREBBP (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to KIAA1240 (unknown origin) assessed as dissociation constant by bromoKdselect analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to biotinylated C-terminal Avi/His-TEV-fused BRD9 (unknown origin) expressed in Escherichia coli by isothermal titration calorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183561(CHEMBL3824146)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183561(CHEMBL3824146)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
LigandPNGBDBM50183563(CHEMBL3823697)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using acetylated H4 K5/8/12/16 as substrate incubated for 60 mins by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)