Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50027216
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.0110nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.0660nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.0660nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  1.82nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  18nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  23.3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  23.3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  80nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  260nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  2.07E+3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed