Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50029437
LigandChemical structure of BindingDB Monomer ID 50403384BDBM50403384(CHEMBL17445)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50230001BDBM50230001(4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403407BDBM50403407(CHEMBL17210)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 13531BDBM13531(4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50104352BDBM50104352(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 13336BDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403386BDBM50403386(CHEMBL417087)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403376BDBM50403376(CHEMBL17389)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50104373BDBM50104373(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403397BDBM50403397(CHEMBL17334)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284507BDBM50284507(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403404BDBM50403404(CHEMBL17346)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284506BDBM50284506(4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403392BDBM50403392(CHEMBL17293)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403402BDBM50403402(CHEMBL17493)
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284483BDBM50284483((3-{4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imida...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50104356BDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284513BDBM50284513({4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284516BDBM50284516(2,4,5-Triarylimidazole analogue | CHEMBL16925)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50104355BDBM50104355(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50104351BDBM50104351(4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imi...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284487BDBM50284487((1Z)-N'-cyano-2-{4-[4-(4-fluorophenyl)-5-pyridin-4...)
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284492BDBM50284492(4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403381BDBM50403381(CHEMBL17480)
Affinity DataIC50: 440nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403377BDBM50403377(CHEMBL17224)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50110200BDBM50110200(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403398BDBM50403398(CHEMBL17688)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50075778BDBM50075778(4-[5-(4-Fluoro-phenyl)-2-(4-methylsulfanyl-phenyl)...)
Affinity DataIC50: 580nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403399BDBM50403399(CHEMBL17238)
Affinity DataIC50: 590nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403394BDBM50403394(CHEMBL17252)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284489BDBM50284489(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403382BDBM50403382(CHEMBL17273)
Affinity DataIC50: 620nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403400BDBM50403400(CHEMBL17204)
Affinity DataIC50: 640nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403375BDBM50403375(CHEMBL276114)
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403408BDBM50403408(CHEMBL275365)
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403391BDBM50403391(CHEMBL17220)
Affinity DataIC50: 680nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403409BDBM50403409(CHEMBL276529)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284495BDBM50284495(CHEMBL16911 | 4-[5-(4-Fluoro-phenyl)-2-(4-methanes...)
Affinity DataIC50: 710nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403379BDBM50403379(CHEMBL277587)
Affinity DataIC50: 710nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403395BDBM50403395(CHEMBL17792)
Affinity DataIC50: 740nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403403BDBM50403403(CHEMBL16926)
Affinity DataIC50: 740nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50217610BDBM50217610(4-(2-(4-(methylsulfinyl)phenyl)-4-(naphthalen-2-yl...)
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284481BDBM50284481(Benzyl-{4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl-1H-i...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against 5-lipoxygenase enzyme from RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403396BDBM50403396(CHEMBL16838)
Affinity DataIC50: 820nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403383BDBM50403383(CHEMBL280457)
Affinity DataIC50: 860nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403393BDBM50403393(CHEMBL17641)
Affinity DataIC50: 930nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284475BDBM50284475(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403380BDBM50403380(CHEMBL17135)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50403385BDBM50403385(CHEMBL17482)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50284481BDBM50284481(Benzyl-{4-[4-(4-fluoro-phenyl)-5-pyridin-4-yl-1H-i...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

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