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Found 4 Enz. Inhib. hit(s) with all data for entry = 50029525
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036133(7-ethyl-7-hydroxy-(7S)-7,8,11,13-tetrahydro-10H-[1...)
Affinity DataIC50:  30nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285229(7-ethyl-7-hydroxy-(7S)-7,8,11,13-tetrahydro-10H-[1...)
Affinity DataIC50:  150nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285230((S)-9-Amino-4-ethyl-4,8-dihydroxy-1,12-dihydro-4H-...)
Affinity DataIC50:  170nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50:  700nMAssay Description:Ability to inhibit calf thymus topoisomerase I when assayed in the cleavable complex formationMore data for this Ligand-Target Pair