Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50029730
TargetMu-type opioid receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  0.210nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  0.530nMAssay Description:Compound was tested for Inhibition of 9 (1nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50:  0.560nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  1.5nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  5.80nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50:  24nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50:  26nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50:  45nMAssay Description:Compound was tested for Inhibition of 9 (1nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50:  177nMAssay Description:Compound was tested for Inhibition of 9 (1nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  178nMAssay Description:Compound was tested for Inhibition of 9 (1nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  184nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50:  501nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In DepthDetails Article