Compile Data Set for Download or QSAR
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Found 30 Enz. Inhib. hit(s) with all data for entry = 50029822
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288331(4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochrome...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288322(4-(8-Fluoro-7-methoxy-3-trifluoromethyl-5H-isothio...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288325(4-(7-Methoxy-3-trifluoromethyl-5H-isothiochromeno[...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288333(4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothioc...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288323(4-(3-Trifluoromethyl-5H-isothiochromeno[4,3-c]pyra...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288334(4-(8-Fluoro-3-trifluoromethyl-5H-isothiochromeno[4...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288329(4-(7-Methyl-3-trifluoromethyl-5H-isothiochromeno[4...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288321(4-(3-Difluoromethyl-8-fluoro-7-methoxy-5H-isothioc...)
Affinity DataIC50:  32nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288330(4-(7-Fluoro-3-trifluoromethyl-5H-isothiochromeno[4...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288326(8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-...)
Affinity DataIC50:  75nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288324(4-(3-Cyano-7-fluoro-5H-isothiochromeno[4,3-c]pyraz...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288330(4-(7-Fluoro-3-trifluoromethyl-5H-isothiochromeno[4...)
Affinity DataIC50:  270nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288325(4-(7-Methoxy-3-trifluoromethyl-5H-isothiochromeno[...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288323(4-(3-Trifluoromethyl-5H-isothiochromeno[4,3-c]pyra...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288327(4-(3-Trifluoromethyl-4H-thiochromeno[4,3-c]pyrazol...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288324(4-(3-Cyano-7-fluoro-5H-isothiochromeno[4,3-c]pyraz...)
Affinity DataIC50:  760nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288329(4-(7-Methyl-3-trifluoromethyl-5H-isothiochromeno[4...)
Affinity DataIC50:  790nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288335(4-(3-Trifluoromethyl-4,5-dihydro-benzo[g]indazol-1...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288328(4-(8-Fluoro-7-methoxy-4-oxo-3-trifluoromethyl-4,5-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288331(4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochrome...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288322(4-(8-Fluoro-7-methoxy-3-trifluoromethyl-5H-isothio...)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288334(4-(8-Fluoro-3-trifluoromethyl-5H-isothiochromeno[4...)
Affinity DataIC50:  6.24E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288332(4-(3-Trifluoromethyl-4H-chromeno[4,3-c]pyrazol-1-y...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288327(4-(3-Trifluoromethyl-4H-thiochromeno[4,3-c]pyrazol...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288333(4-(8-Fluoro-7-methyl-3-trifluoromethyl-5H-isothioc...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288335(4-(3-Trifluoromethyl-4,5-dihydro-benzo[g]indazol-1...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288326(8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288321(4-(3-Difluoromethyl-8-fluoro-7-methoxy-5H-isothioc...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288328(4-(8-Fluoro-7-methoxy-4-oxo-3-trifluoromethyl-4,5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails Article