Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50029928
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289397BDBM50289397(3-[(1-{3-Methyl-2-[(naphthalene-2-carbonyl)-amino]...)
Affinity DataKi:  0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289410BDBM50289410(Peptidic phenyl ketoether analogue | CHEMBL26544)
Affinity DataKi:  0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289398BDBM50289398(Peptidic phenyl ketoether analogue | CHEMBL553107)
Affinity DataKi:  0.200nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289405BDBM50289405(Peptidic phenyl ketoether analogue | CHEMBL2371932)
Affinity DataKi:  1.10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084633BDBM50084633(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2,3...)
Affinity DataKi:  1.30nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289402BDBM50289402((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289412BDBM50289412((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.5nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091577BDBM50091577(3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289393BDBM50289393((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289407BDBM50289407((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  2nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289388BDBM50289388((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  2.20nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289408BDBM50289408((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  5.30nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289400BDBM50289400((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  7nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289403BDBM50289403((S)-3-(3-Methoxy-2-{3-[(naphthalene-2-carbonyl)-am...)
Affinity DataKi:  7.10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289387BDBM50289387((S)-3-(2-{6-Benzyl-3-[(naphthalene-1-carbonyl)-ami...)
Affinity DataKi:  10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289409BDBM50289409((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  14nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289395BDBM50289395((S)-3-(2-{6-Butyl-3-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  16nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289411BDBM50289411((S)-3-(3-Methyl-2-{3-[(naphthalene-1-carbonyl)-ami...)
Affinity DataKi:  21nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289404BDBM50289404((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  25nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289390BDBM50289390((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  39nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289399BDBM50289399((S)-3-(2-{6-Ethyl-3-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289414BDBM50289414((S)-3-(2-{6-Hexyl-3-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289415BDBM50289415((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  45nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289394BDBM50289394((S)-3-(2-{2-Butyl-5-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  46nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289401BDBM50289401((S)-3-(2-{5-[(Naphthalene-1-carbonyl)-amino]-6-oxo...)
Affinity DataKi:  66nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289386BDBM50289386((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  68nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289396BDBM50289396((S)-3-(2-{6-Methyl-3-[(naphthalene-1-carbonyl)-ami...)
Affinity DataKi:  95nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289413BDBM50289413((S)-3-(2-{6-Methyl-3-[(naphthalene-2-carbonyl)-ami...)
Affinity DataKi:  160nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289391BDBM50289391((S)-3-[2-(3-Benzoylamino-6-methyl-2-oxo-2H-pyridin...)
Affinity DataKi:  530nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289406BDBM50289406((S)-3-[2-(3-Benzyloxycarbonylamino-6-methyl-2-oxo-...)
Affinity DataKi:  590nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289389BDBM50289389((S)-3-(2-{6-Methyl-3-[(naphthalene-2-carbonyl)-ami...)
Affinity DataKi:  2.20E+3nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289392BDBM50289392((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  7.20E+3nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article