Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50030049
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290631BDBM50290631((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-4-yl-a...)
Affinity DataIC50: 6.40nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4626BDBM4626(CHEMBL301018 | N-(3-chloro-4-fluorophenyl)-6,7-dim...)
Affinity DataIC50: 9nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290640BDBM50290640((6,7-Dimethoxy-quinazolin-4-yl)-(2-phenyl-cyclopro...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4626BDBM4626(CHEMBL301018 | N-(3-chloro-4-fluorophenyl)-6,7-dim...)
Affinity DataIC50: 80nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290632BDBM50290632(Acetic acid 7-methoxy-4-(2-phenyl-cyclopropylamino...)
Affinity DataIC50: 84nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290640BDBM50290640((6,7-Dimethoxy-quinazolin-4-yl)-(2-phenyl-cyclopro...)
Affinity DataIC50: 140nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290641BDBM50290641((6,7-Dimethoxy-quinazolin-4-yl)-(3-methyl-benzyl)-...)
Affinity DataIC50: 170nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290637BDBM50290637((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-1-yl-a...)
Affinity DataIC50: 200nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290642BDBM50290642([7-Methoxy-6-(2-morpholin-4-yl-ethoxy)-quinazolin-...)
Affinity DataIC50: 300nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290638BDBM50290638([6-(3-Dimethylamino-propoxy)-7-methoxy-quinazolin-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290638BDBM50290638([6-(3-Dimethylamino-propoxy)-7-methoxy-quinazolin-...)
Affinity DataIC50: 310nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290631BDBM50290631((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-4-yl-a...)
Affinity DataIC50: 360nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290643BDBM50290643(7-Methoxy-4-(2-phenyl-cyclopropylamino)-quinazolin...)
Affinity DataIC50: 390nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290635BDBM50290635(N-(3-Chloro-4-fluoro-phenyl)-N'-(6,7-dimethoxy-qui...)
Affinity DataIC50: 430nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290642BDBM50290642([7-Methoxy-6-(2-morpholin-4-yl-ethoxy)-quinazolin-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290634BDBM50290634((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-3-yl-a...)
Affinity DataIC50: 660nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290630BDBM50290630((3-Chloro-4-fluoro-phenyl)-(6,7-dimethoxy-quinazol...)
Affinity DataIC50: 730nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290635BDBM50290635(N-(3-Chloro-4-fluoro-phenyl)-N'-(6,7-dimethoxy-qui...)
Affinity DataIC50: 780nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290644BDBM50290644((6,7-Dimethoxy-quinazolin-4-yl)-quinoxalin-2-yl-am...)
Affinity DataIC50: 780nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290634BDBM50290634((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-3-yl-a...)
Affinity DataIC50: 810nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290633BDBM50290633(CHEMBL328277 | CHEMBL545776 | 4-(2,3-Dihydro-indol...)
Affinity DataIC50: 820nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290639BDBM50290639(Benzo[1,2,4]triazin-3-yl-(6,7-dimethoxy-quinazolin...)
Affinity DataIC50: 820nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290641BDBM50290641((6,7-Dimethoxy-quinazolin-4-yl)-(3-methyl-benzyl)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290636BDBM50290636((6,7-Dimethoxy-quinazolin-4-yl)-indan-1-yl-amine |...)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290636BDBM50290636((6,7-Dimethoxy-quinazolin-4-yl)-indan-1-yl-amine |...)
Affinity DataIC50: 1.73E+3nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290637BDBM50290637((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-1-yl-a...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290630BDBM50290630((3-Chloro-4-fluoro-phenyl)-(6,7-dimethoxy-quinazol...)
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290633BDBM50290633(CHEMBL328277 | CHEMBL545776 | 4-(2,3-Dihydro-indol...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290632BDBM50290632(Acetic acid 7-methoxy-4-(2-phenyl-cyclopropylamino...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290639BDBM50290639(Benzo[1,2,4]triazin-3-yl-(6,7-dimethoxy-quinazolin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290643BDBM50290643(7-Methoxy-4-(2-phenyl-cyclopropylamino)-quinazolin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290644BDBM50290644((6,7-Dimethoxy-quinazolin-4-yl)-quinoxalin-2-yl-am...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article