Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50030758
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300929BDBM50300929((S)-2-amino-3-(4-(4-amino-6-(biphenyl-2-ylmethylam...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300932BDBM50300932((S)-2-amino-3-(4-(4-amino-6-((4'-methylbiphenyl-4-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300935BDBM50300935((S)-3-{4-[4-(1-Adamantan-1-yl-ethylamino)-6-amino-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243613BDBM50243613((S)-2-amino-3-(4-(4-amino-6-(naphthalen-2-ylmethyl...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300934BDBM50300934((2S)-2-amino-3-(4-(4-amino-6-(1-(biphenyl-4-yl)eth...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243020BDBM50243020((S)-2-amino-3-(4-(4-amino-6-((R)-1-(naphthalen-2-y...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300930BDBM50300930((S)-2-amino-3-(4-(4-amino-6-(biphenyl-3-ylmethylam...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300936BDBM50300936((S)-2-amino-3-(4-(4-amino-6-((S)-1-(naphthalen-2-y...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300940BDBM50300940((S)-2-amino-3-(4-(4-amino-6-(methyl((R)-1-(naphtha...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300937BDBM50300937((S)-2-amino-3-(4-(4-amino-6-(2-(naphthalen-2-yl)pr...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300928BDBM50300928((S)-2-amino-3-(4-(4-amino-6-(biphenyl-4-ylmethylam...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300925BDBM50300925((S)-2-amino-3-(4-(4-amino-6-(3,4-dimethylbenzylami...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300924BDBM50300924((S)-2-amino-3-(4-(4-amino-6-(cyclohexylmethylamino...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300942BDBM50300942((2S)-2-amino-3-(4-(4-amino-6-(3-methyl-1-(naphthal...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300926BDBM50300926((S)-2-amino-3-(4-(4-amino-6-(4-(trifluoromethyl)be...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300941BDBM50300941((2S)-2-amino-3-(4-(4-amino-6-(1-(naphthalen-2-yl)p...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300931BDBM50300931((S)-2-amino-3-(4-(4-amino-6-(4-phenoxybenzylamino)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300933BDBM50300933((S)-2-amino-3-(4-(4-amino-6-((4'-(trifluoromethyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300946BDBM50300946((2S)-2-amino-3-(4-(4-(1-(naphthalen-2-yl)ethylamin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300943BDBM50300943((2S)-2-amino-3-(4-(4-amino-6-(2-methyl-1-(naphthal...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300938BDBM50300938((2S)-2-amino-3-(4-(4-amino-6-(2,2,2-trifluoro-1-(n...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300939BDBM50300939((2S)-2-amino-3-(4-(4-amino-6-(2,2,2-trifluoro-1-(n...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300927BDBM50300927((S)-2-amino-3-(4-(4-amino-6-(benzylamino)-1,3,5-tr...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300945BDBM50300945((S)-2-amino-3-(4-(4-(methylamino)-6-((R)-1-(naphth...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300944BDBM50300944((S)-2-amino-3-(4-(4-morpholino-6-(naphthalen-2-ylm...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed