Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50031162
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118242BDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50423774BDBM50423774(CHEMBL2309024)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at P2Y1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308336BDBM50308336({[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31995BDBM31995(ADP | CHEMBL14830 | Adenosine Diphosphate (ADP))
Affinity DataEC50:  14nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268012BDBM50268012({[({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2BDBM2(CHEMBL14249 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-pu...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at P2Y1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308334BDBM50308334(Di-(2-MeS)-adenosine 5',5''-P1,P4,alpha,beta-Methy...)
Affinity DataEC50:  420nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308335BDBM50308335(Di-(2-MeS)-adenosine 5',5''-P1,P4,beta,gamma-Methy...)
Affinity DataEC50:  460nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed