Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50032387
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328416((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328417((Z)-4,5-difluoro-3-((3-methyl-4-(3-morpholinopropo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328406((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50: 12nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328419((Z)-3-((4-(3-(diethylamino)propoxy)-3-methylazulen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 15nMAssay Description:Inhibition of c-Kit autophosphorylation in human Kasumi-1 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 16nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328418((Z)-4,5-difluoro-3-((3-methyl-4-(3-(piperidin-1-yl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328415((Z)-3-((4-(2-(4-(dimethylamino)piperidin-1-yl)etho...)
Affinity DataIC50: 18nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328403((Z)-5-fluoro-3-((3-methyl-4-(2-morpholinoethoxy)az...)
Affinity DataIC50: 19nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328401((Z)-5-fluoro-3-((3-fluoroazulen-1-yl)methylene)ind...)
Affinity DataIC50: 23nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328405((E)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50: 25nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydroxymethyl)pyrrol...)
Affinity DataIC50: 28nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328407((E)-3-((4-(3-(diethylamino)propoxy)-3-methylazulen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328408((Z)-3-((4-(3-(diethylamino)propoxy)-3-methylazulen...)
Affinity DataIC50: 39nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydroxymethyl)pyrrol...)
Affinity DataIC50: 44nMAssay Description:Inhibition of c-Kit autophosphorylation in human Kasumi-1 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 53nMAssay Description:Inhibition of KDR autophosphorylation in HUVEC by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328399((E)-5-fluoro-3-((3-methylazulen-1-yl)methylene)ind...)
Affinity DataIC50: 60nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydroxymethyl)pyrrol...)
Affinity DataIC50: 70nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328411((Z)-5-bromo-3-((3-methyl-4-(3-morpholinopropoxy)az...)
Affinity DataIC50: 86nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328410((Z)-5-fluoro-3-((3-methyl-4-(3-morpholinopropoxy)a...)
Affinity DataIC50: 90nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydroxymethyl)pyrrol...)
Affinity DataIC50: 98nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328400((Z)-5-fluoro-3-((3-methylazulen-1-yl)methylene)ind...)
Affinity DataIC50: 128nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328413((E)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50: 177nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328414(E/Z-(S)-5-fluoro-3-((4-(2-(2-(hydroxymethyl)pyrrol...)
Affinity DataIC50: 186nMAssay Description:Inhibition of KDR autophosphorylation in HUVEC by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328404((Z)-5-fluoro-3-((3-methyl-4-(3-morpholinopropoxy)a...)
Affinity DataIC50: 224nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328392(3-(azulen-1-ylmethylene)indolin-2-one | CHEMBL1257...)
Affinity DataIC50: 470nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328412((E)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50: 742nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328402((Z)-3-(azulen-1-ylmethylene)-N,N-dimethyl-2-oxoind...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328396((Z)-3-(azulen-1-ylmethylene)-5-methylindolin-2-one...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328397((E)-3-((3-methylazulen-1-yl)methylene)indolin-2-on...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328398((Z)-3-((3-methylazulen-1-yl)methylene)indolin-2-on...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328393((Z)-3-(azulen-1-ylmethylene)-5-fluoroindolin-2-one...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328394((E)-3-(azulen-1-ylmethylene)-5-bromoindolin-2-one ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328395((Z)-3-(azulen-1-ylmethylene)-5-bromoindolin-2-one ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Industrial Technology Research Institute

Curated by ChEMBL
LigandPNGBDBM50328409((Z)-3-((4-(3-(dimethylamino)propoxy)-3-methylazule...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of FLT3 by time resolved fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed