Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50033425
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345085((2S)-N-(3-(1-aminoisoquinolin-6-yl)-1-oxo-1-(piper...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345082(1-(1,4-diazepan-1-yl)-2-(5-methoxy-1-(4-methoxy-2,...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345071((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345084(2-(5-fluoro-1-(4-methoxy-2,3-dimethylphenylsulfony...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345081((1,4-diazepan-1-yl)(5-fluoro-1-(4-methoxy-2,3-dime...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345082(1-(1,4-diazepan-1-yl)-2-(5-methoxy-1-(4-methoxy-2,...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345083(2-(5-fluoro-1-(4-methoxy-2,3-dimethylphenylsulfony...)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345079((1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345070((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345078(1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-...)
Affinity DataKi:  560nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345069((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345080((1,4-diazepan-1-yl)(1-(4-methoxy-2,3-dimethylpheny...)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345075((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345077(1-(4-methoxy-2,3-dimethylphenylsulfonyl)-N-(3-(4-m...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345074((S)-N-(3-(dimethylamino)propyl)-2-(4-methoxy-2,3,6...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345072((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345076((S)-4-methoxy-2,3,6-trimethyl-N-(1-(4-methyl-1,4-d...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345073((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1A receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345067((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345066((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345065((S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataIC50:  371nMAssay Description:Antagonist activity at human vasopressin V1B receptor expressed in CHO cells assessed as inhibition of AVP-induced calcium mobilisation by luciferase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed