Compile Data Set for Download or QSAR
Report error Found 140 Enz. Inhib. hit(s) with all data for entry = 50033436
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345312BDBM50345312(Ethyl 5-cyano-6-{4-[(2-naphthylamino)carbonyl]pipe...)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345326BDBM50345326(Ethyl 5-chloro-6-{4-[(1-naphthylamino)carbonyl]pip...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345326BDBM50345326(Ethyl 5-chloro-6-{4-[(1-naphthylamino)carbonyl]pip...)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345265BDBM50345265(Ethyl 5-cyano-6-(4-{[(4-fluorobenzyl)amino]carbony...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345318BDBM50345318(Ethyl 5-chloro-6-(4-{[(3-chlorophenyl)amino]carbon...)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345303BDBM50345303(Ethyl 5-cyano-6-(4-{[(3-methylphenyl)amino]carbony...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345266BDBM50345266(Ethyl 5-cyano-6-(4-{[(4-methylbenzyl)amino]carbony...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345312BDBM50345312(Ethyl 5-cyano-6-{4-[(2-naphthylamino)carbonyl]pipe...)
Affinity DataIC50: 190nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345269BDBM50345269(Ethyl 5-cyano-6-[4-({[(1S)-1-phenylethyl]amino}car...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345311BDBM50345311(Ethyl 5-cyano-6-(4-{[(3,4-dichlorophenyl)amino]car...)
Affinity DataIC50: 190nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345303BDBM50345303(Ethyl 5-cyano-6-(4-{[(3-methylphenyl)amino]carbony...)
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345302BDBM50345302(Ethyl 6-(4-{[(3-chlorophenyl)amino]carbonyl}pipera...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345311BDBM50345311(Ethyl 5-cyano-6-(4-{[(3,4-dichlorophenyl)amino]car...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345319BDBM50345319(Ethyl 5-chloro-6-(4-{[(3-methylphenyl)amino]carbon...)
Affinity DataIC50: 240nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345263BDBM50345263(Ethyl 5-cyano-6-(4-{[(3-fluorobenzyl)amino]carbony...)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345268BDBM50345268(Ethyl 5-cyano-6-(4-{[(3,4-dichlorobenzyl)amino]car...)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345329BDBM50345329(Ethyl 6-{4-[(benzylamino)carbonyl]piperazin-1-yl}-...)
Affinity DataIC50: 270nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345318BDBM50345318(Ethyl 5-chloro-6-(4-{[(3-chlorophenyl)amino]carbon...)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345306BDBM50345306(Ethyl 6-(4-{[(4-chlorophenyl)amino]carbonyl}pipera...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345306BDBM50345306(Ethyl 6-(4-{[(4-chlorophenyl)amino]carbonyl}pipera...)
Affinity DataIC50: 310nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345305BDBM50345305(Ethyl 5-cyano-6-(4-{[(3-methoxyphenyl)amino]carbon...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345287BDBM50345287(Ethyl 6-[4-(anilinocarbonyl)piperazin-1-yl]-5-cyan...)
Affinity DataIC50: 320nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345266BDBM50345266(Ethyl 5-cyano-6-(4-{[(4-methylbenzyl)amino]carbony...)
Affinity DataIC50: 320nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345269BDBM50345269(Ethyl 5-cyano-6-[4-({[(1S)-1-phenylethyl]amino}car...)
Affinity DataIC50: 330nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345330BDBM50345330(Ethyl 6-(4-{[(2-chlorobenzyl)amino]carbonyl}pipera...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345331BDBM50345331(Ethyl 5-cyano-6-(4-{[(2-methylbenzyl)amino]carbony...)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345327BDBM50345327(Ethyl 5-chloro-6-{4-[(2-naphthylamino)carbonyl]pip...)
Affinity DataIC50: 380nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345327BDBM50345327(Ethyl 5-chloro-6-{4-[(2-naphthylamino)carbonyl]pip...)
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345319BDBM50345319(Ethyl 5-chloro-6-(4-{[(3-methylphenyl)amino]carbon...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345267BDBM50345267(Ethyl 5-cyano-6-(4-{[(4-methoxybenzyl)amino]carbon...)
Affinity DataIC50: 430nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345278BDBM50345278(Ethyl 5-chloro-6-(4-{[(3,4-dichlorobenzyl)amino]ca...)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345264BDBM50345264(Ethyl 5-cyano-6-(4-{[(3-methylbenzyl)amino]carbony...)
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345276BDBM50345276(Ethyl 5-chloro-6-(4-{[(4-methylbenzyl)amino]carbon...)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345265BDBM50345265(Ethyl 5-cyano-6-(4-{[(4-fluorobenzyl)amino]carbony...)
Affinity DataIC50: 470nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345268BDBM50345268(Ethyl 5-cyano-6-(4-{[(3,4-dichlorobenzyl)amino]car...)
Affinity DataIC50: 480nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345270BDBM50345270(Ethyl 5-cyano-6-[4-({[1-(3-isopropenylphenyl)-1-me...)
Affinity DataIC50: 490nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345302BDBM50345302(Ethyl 6-(4-{[(3-chlorophenyl)amino]carbonyl}pipera...)
Affinity DataIC50: 490nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345330BDBM50345330(Ethyl 6-(4-{[(2-chlorobenzyl)amino]carbonyl}pipera...)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345331BDBM50345331(Ethyl 5-cyano-6-(4-{[(2-methylbenzyl)amino]carbony...)
Affinity DataIC50: 510nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345329BDBM50345329(Ethyl 6-{4-[(benzylamino)carbonyl]piperazin-1-yl}-...)
Affinity DataIC50: 580nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345280BDBM50345280(Ethyl 5-chloro-6-[4-({[1-(3-isopropenylphenyl)-1-m...)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345270BDBM50345270(Ethyl 5-cyano-6-[4-({[1-(3-isopropenylphenyl)-1-me...)
Affinity DataIC50: 590nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345321BDBM50345321(Ethyl 5-chloro-6-(4-{[(4-chlorophenyl)amino]carbon...)
Affinity DataIC50: 600nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345322BDBM50345322(Ethyl 5-chloro-6-(4-{[(4-methylphenyl)amino]carbon...)
Affinity DataIC50: 600nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345280BDBM50345280(Ethyl 5-chloro-6-[4-({[1-(3-isopropenylphenyl)-1-m...)
Affinity DataIC50: 610nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345267BDBM50345267(Ethyl 5-cyano-6-(4-{[(4-methoxybenzyl)amino]carbon...)
Affinity DataIC50: 640nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345287BDBM50345287(Ethyl 6-[4-(anilinocarbonyl)piperazin-1-yl]-5-cyan...)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345272BDBM50345272(Ethyl 5-chloro-6-(4-{[(2-methylbenzyl)amino]carbon...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345264BDBM50345264(Ethyl 5-cyano-6-(4-{[(3-methylbenzyl)amino]carbony...)
Affinity DataIC50: 750nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50345281BDBM50345281(Ethyl 5-cyano-6-(4-((1R,2S)-2-phenylcyclopropylcar...)
Affinity DataIC50: 760nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
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