Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50033462
TargetAcetylcholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345813(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((S)-1-p...)
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 179nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345812(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...)
Affinity DataIC50: 302nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345813(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((S)-1-p...)
Affinity DataIC50: 334nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345810(3-((S)-1-(dimethylamino)ethyl)phenyl(R)-1-phenylpr...)
Affinity DataIC50: 404nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345810(3-((S)-1-(dimethylamino)ethyl)phenyl(R)-1-phenylpr...)
Affinity DataIC50: 416nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345811(3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpr...)
Affinity DataIC50: 508nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345811(3-((S)-1-(dimethylamino)ethyl)phenyl(S)-1-phenylpr...)
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sention

Curated by ChEMBL
LigandPNGBDBM50345812(3-((S)-1-(dimethylamino)ethyl)phenylmethyl((R)-1-p...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed