Compile Data Set for Download or QSAR
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Found 17 Enz. Inhib. hit(s) with all data for entry = 50034900
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.0900nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]DIDI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.330nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290387(22-cyclopropylmethyl-2-ethoxy-13-methyl-14-oxa-11,...)
Affinity DataKi:  0.780nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50121334(2-ethoxy-13,22-dimethyl-(2S,13R)-14-oxa-11,22-diaz...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50121334(2-ethoxy-13,22-dimethyl-(2S,13R)-14-oxa-11,22-diaz...)
Affinity DataKi:  8.81nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]DIDI as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Affinity DataKi:  11nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor delta 1 in rat brain homogenates using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290387(22-cyclopropylmethyl-2-ethoxy-13-methyl-14-oxa-11,...)
Affinity DataKi:  14nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  14nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]CI977 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  30nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Affinity DataKi:  30nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290387(22-cyclopropylmethyl-2-ethoxy-13-methyl-14-oxa-11,...)
Affinity DataKi:  39nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290387(22-cyclopropylmethyl-2-ethoxy-13-methyl-14-oxa-11,...)
Affinity DataKi:  59nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50121334(2-ethoxy-13,22-dimethyl-(2S,13R)-14-oxa-11,22-diaz...)
Affinity DataKi:  286nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Affinity DataKi:  667nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50121334(2-ethoxy-13,22-dimethyl-(2S,13R)-14-oxa-11,22-diaz...)
Affinity DataKi:  715nMAssay Description:Compound was evaluated for the binding affinity towards mu opioid receptor in rat brain homogenates using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50290388(22-allyl-2-ethoxy-13-methyl-14-oxa-11,22-diazahept...)
Affinity DataKi:  765nMAssay Description:Compound was evaluated for the binding affinity towards Opioid receptor kappa 1 in rat brain homogenates using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50121334(2-ethoxy-13,22-dimethyl-(2S,13R)-14-oxa-11,22-diaz...)
Affinity DataEC50:  104nMAssay Description:Compound was evaluated in 3 determinations for the agonistic activity in the Opioid receptor delta 1 of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article