Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50035157
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104502BDBM50104502(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104502BDBM50104502(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 260nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through fibrin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104505BDBM50104505(9-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 390nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104502BDBM50104502(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 510nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104511BDBM50104511(7-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 520nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104514BDBM50104514(5-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 1.75E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104504BDBM50104504(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 1.93E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104503BDBM50104503(Thiophene-2-carboxylic acid {4-[5-[1-[5-(2-dimethy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104518BDBM50104518(CHEMBL544314 | CHEMBL40180 | 3-[1-[5-(2-Dimethylam...)
Affinity DataIC50: 3.50E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104507BDBM50104507(7-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50: 4.77E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104524BDBM50104524(N-{4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thio...)
Affinity DataIC50: 6.10E+3nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104512BDBM50104512(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50: 1.09E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104506BDBM50104506(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50: 1.24E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104510BDBM50104510(3-[1-(4-Bromo-phenyl)-meth-(Z)-ylidene]-6-[1-[5-(2...)
Affinity DataIC50: 1.31E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104522BDBM50104522(5-{4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-pipe...)
Affinity DataIC50: 1.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104525BDBM50104525(4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophe...)
Affinity DataIC50: 1.77E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104515BDBM50104515(4-{4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-pipe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104523BDBM50104523(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104509BDBM50104509(3-[1-[5-(2-Dimethylamino-ethanesulfinyl)-thiophen-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104508BDBM50104508({4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-pipera...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104520BDBM50104520(3-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-6-[1-[5-(2...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104521BDBM50104521(4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-piperaz...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104519BDBM50104519(3-[1-[5-(2-Dimethylamino-ethoxy)-thiophen-2-yl]-me...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104516BDBM50104516(3-[1-(3-Chloro-phenyl)-meth-(Z)-ylidene]-6-[1-[5-(...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104517BDBM50104517(4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetPlasminogen activator inhibitor 1(Human)
Xenova

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104513BDBM50104513(3-[1-[5-(2-Diethylamino-ethylsulfanyl)-thiophen-2-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed