Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50035382
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322362BDBM50322362(2-(4-((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...)
Affinity DataIC50: 45nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366893BDBM50366893(CHEMBL607649)
Affinity DataIC50: 100nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366900BDBM50366900(CHEMBL608792)
Affinity DataIC50: 250nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366902BDBM50366902(CHEMBL607648)
Affinity DataIC50: 450nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366904BDBM50366904(CHEMBL607928)
Affinity DataIC50: 700nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366895BDBM50366895(CHEMBL607633)
Affinity DataIC50: 700nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366901BDBM50366901(CHEMBL608232)
Affinity DataIC50: 900nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366897BDBM50366897(CHEMBL607650)
Affinity DataIC50: 1.90E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366898BDBM50366898(CHEMBL608784)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366903BDBM50366903(CHEMBL607634)
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137382BDBM50137382(2-(6-Methylamino-purin-9-yl)-N-(1-oxo-2,3-dihydro-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366892BDBM50366892(CHEMBL608783)
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137371BDBM50137371(2-Benzoimidazol-1-yl-N-(1-oxo-2,3-dihydro-1H-isoin...)
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137378BDBM50137378(N-[(3S,4R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-te...)
Affinity DataIC50: 5.00E+3nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366899BDBM50366899(CHEMBL607657)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137376BDBM50137376(N-(1-Oxo-2,3-dihydro-1H-isoindol-4-yl)-2-piperazin...)
Affinity DataIC50: 1.80E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137359BDBM50137359(2-Ethylamino-N-(1-oxo-2,3-dihydro-1H-isoindol-4-yl...)
Affinity DataIC50: 1.80E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137368BDBM50137368(2-Diethylamino-N-(1-oxo-2,3-dihydro-1H-isoindol-4-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137366BDBM50137366(Isoindol-1-one | CHEMBL352926)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137380BDBM50137380(2-(4-Methyl-piperazin-1-yl)-N-(1-oxo-2,3-dihydro-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137377BDBM50137377(2-Methylamino-N-(1-oxo-2,3-dihydro-1H-isoindol-4-y...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137358BDBM50137358(2-Morpholin-4-yl-N-(1-oxo-2,3-dihydro-1H-isoindol-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137375BDBM50137375(8-Methylamino-octanoic acid (1-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137369BDBM50137369(2-(3,4-Dihydro-1H-isoquinolin-2-yl)-N-(1-oxo-2,3-d...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137374BDBM50137374(4-Amino-2,3-dihydro-isoindol-1-one | CHEMBL169140)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137385BDBM50137385(3-(4-Methyl-piperazin-1-yl)-N-(1-oxo-2,3-dihydro-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366894BDBM50366894(CHEMBL608508)
Affinity DataIC50: 6.80E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50137372BDBM50137372(N-[(3S,4R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-te...)
Affinity DataIC50: 7.50E+4nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Mouse)
Inotek Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366896BDBM50366896(CHEMBL608772)
Affinity DataIC50: 3.00E+5nMAssay Description:Tested for inhibition of poly(ADP-ribose) polymerase-1 (PARP-1) in mouse using Cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed