Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50036033
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001176BDBM50001176(CHEMBL320274 | 2-(5-Chloro-benzothiazol-2-ylsulfan...)
Affinity DataEC50:  20nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001187BDBM50001187(CHEMBL110928 | 3-(5-Chloro-benzothiazol-2-ylsulfan...)
Affinity DataEC50:  20nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001181BDBM50001181(CHEMBL108204 | 3-(Benzothiazol-2-ylsulfanyl)-N-hyd...)
Affinity DataEC50:  39nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001171BDBM50001171(CHEMBL419745 | 3-(Benzothiazol-2-ylsulfanyl)-propy...)
Affinity DataEC50:  45nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001168BDBM50001168(CHEMBL108854 | 3-(Benzothiazol-2-ylsulfanyl)-propy...)
Affinity DataEC50:  70nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001182BDBM50001182(CHEMBL110863 | 2-(5-Chloro-benzothiazol-2-ylsulfan...)
Affinity DataEC50:  70nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001183BDBM50001183(3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataEC50:  70nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001180BDBM50001180(CHEMBL108624 | 2-(Benzothiazol-2-ylsulfanyl)-N-hyd...)
Affinity DataEC50:  70nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001169BDBM50001169(CHEMBL320329 | 2-benzo[d][1,3]thiazol-2-ylsulfanyl...)
Affinity DataEC50:  90nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001170BDBM50001170(CHEMBL325105 | 5-ethyloxy-2-benzo[d][1,3]thiazol-2...)
Affinity DataEC50:  110nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001179BDBM50001179(CHEMBL110242 | 3-(Benzothiazol-2-ylsulfanyl)-N-hyd...)
Affinity DataEC50:  130nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001172BDBM50001172(CHEMBL320030 | 2-benzo[d][1,3]thiazol-2-ylsulfanyl...)
Affinity DataEC50:  130nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001184BDBM50001184(CHEMBL106206 | 2-(6-Isopropyl-benzothiazol-2-ylsul...)
Affinity DataEC50:  160nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001177BDBM50001177(CHEMBL110327 | 2-(6-Ethoxy-benzothiazol-2-ylsulfan...)
Affinity DataEC50:  390nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataEC50:  470nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001178BDBM50001178(CHEMBL319002 | 2-(7-Chloro-benzothiazol-2-ylsulfan...)
Affinity DataEC50:  530nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001175BDBM50001175(CHEMBL110513 | C-(Benzothiazol-2-ylsulfanyl)-methy...)
Affinity DataEC50:  1.07E+3nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001186BDBM50001186(CHEMBL323039 | 2-(5-Trifluoromethyl-benzothiazol-2...)
Affinity DataEC50:  3.20E+3nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001174BDBM50001174(CHEMBL320275 | 2-(Benzothiazol-2-ylsulfanyl)-ethyl...)
Affinity DataEC50:  5.20E+3nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000540BDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataEC50:  6.80E+3nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001185BDBM50001185(CHEMBL108538 | 2-(5-Chloro-benzothiazol-2-ylsulfan...)
Affinity DataEC50:  2.45E+4nMAssay Description:In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed