Compile Data Set for Download or QSAR
maximum 50k data
Found 69 Enz. Inhib. hit(s) with all data for entry = 50036810
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  0.560nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hSERT cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088338(9-Biphenyl-4-ylmethylene-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  12nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  20nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  20nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088332(9-Thiophen-2-ylmethylene-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  26nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  30nMAssay Description:Compound was evaluated for inhibition of [3H]5-HT uptake in HEK-hSERT cells expressing Human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088326(9-(4-Methoxy-benzylidene)-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  42nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hSERT cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088326(9-(4-Methoxy-benzylidene)-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  53nMAssay Description:Compound was evaluated for inhibition of [3H]5-HT uptake in HEK-hSERT cells expressing Human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  53nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088326(9-(4-Methoxy-benzylidene)-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  56nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  68nMAssay Description:Compound was evaluated for inhibition of [3H]NE uptake in HEK-hNET cells expressing Human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088328(CHEMBL65762 | [9-(3,4-Dichloro-benzylidene)-7-aza-...)
Affinity DataKi:  96nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  108nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088339(9-Furan-2-ylmethylene-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataKi:  111nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088329(9-Naphthalen-1-ylmethylene-7-aza-tricyclo[4.3.1.0*...)
Affinity DataKi:  121nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  155nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088335(9-Furan-3-ylmethylene-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataKi:  164nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088326(9-(4-Methoxy-benzylidene)-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  187nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088326(9-(4-Methoxy-benzylidene)-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  208nMAssay Description:Compound was evaluated for inhibition of [3H]NE uptake in HEK-hNET cells expressing Human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  258nMAssay Description:Compound was evaluated for binding affinity to dopamine transporter using [125I]RTI-55 as a radioligand in HEK cells expressing human transporters.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  264nMAssay Description:Compound was evaluated for inhibition of [3H]NE uptake in HEK-hNET cells expressing Human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088332(9-Thiophen-2-ylmethylene-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  268nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  276nMAssay Description:Compound was evaluated for inhibition of [3H]DA uptake in HEK-hDAT cells expressing Human dopamine TransporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  301nMAssay Description:Compound was evaluated for inhibition of [3H]5-HT uptake in HEK-hSERT cells expressing Human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088333(9-(4-Fluoro-benzylidene)-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  335nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  343nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hSERT cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  423nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088337(Acetic acid 9-benzylidene-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  450nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088338(9-Biphenyl-4-ylmethylene-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  477nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  481nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088335(9-Furan-3-ylmethylene-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataKi:  498nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088333(9-(4-Fluoro-benzylidene)-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  584nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088338(9-Biphenyl-4-ylmethylene-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  614nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  640nMAssay Description:Compound was evaluated for inhibition of [3H]NE uptake in HEK-hNET cells expressing Human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  910nMAssay Description:Compound was evaluated for inhibition of [3H]DA uptake in HEK-hDAT cells expressing Human dopamine TransporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088337(Acetic acid 9-benzylidene-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  1.03E+3nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.04E+3nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hNET cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088337(Acetic acid 9-benzylidene-7-aza-tricyclo[4.3.1.0*3...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088330(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of reuptake of [3H]-NE at Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  1.57E+3nMAssay Description:Compound was evaluated for binding affinity to dopamine transporter using [125I]RTI-55 as a radioligand in HEK cells expressing human transporters.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  1.74E+3nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hNET cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088335(9-Furan-3-ylmethylene-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataKi:  1.88E+3nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  1.92E+3nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088336(9-(3,4-Dichloro-benzylidene)-7-aza-tricyclo[4.3.1....)
Affinity DataKi:  1.92E+3nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088339(9-Furan-2-ylmethylene-7-aza-tricyclo[4.3.1.0*3,7*]...)
Affinity DataKi:  2.02E+3nMAssay Description:Inhibition of reuptake of [3H]DA at Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088332(9-Thiophen-2-ylmethylene-7-aza-tricyclo[4.3.1.0*3,...)
Affinity DataKi:  2.05E+3nMAssay Description:Inhibition of reuptake of [3H]5-HT at serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50088327(9-Benzylidene-7-aza-tricyclo[4.3.1.0*3,7*]decane-2...)
Affinity DataKi:  2.33E+3nMAssay Description:Compound was evaluated for binding affinity using [125I]RTI-55 as a radioligand in HEK-hSERT cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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