Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50039214
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248531BDBM50248531(1-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321645BDBM50321645(1-(3-chloro-5-(5-fluoro-4-(4-fluoro-3-isobutylphen...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321631BDBM50321631(1-(3-chloro-5-(4-(4-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  66nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321632BDBM50321632(1-(3-chloro-5-(5-chloro-4-(4-fluoro-3-(trifluorome...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321630BDBM50321630(1-(3-chloro-5-(5-fluoro-4-(4-fluoro-3-(trifluorome...)
Affinity DataEC50:  89nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321629BDBM50321629(1-(3-chloro-5-(4-(4-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321634BDBM50321634(1-(3-chloro-5-(4-(4-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321633BDBM50321633(1-(3-chloro-5-(5-ethyl-4-(4-fluoro-3-(trifluoromet...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321644BDBM50321644(1-(5-(4-(3-butyl-4-fluorophenyl)-5-fluorothiazol-2...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321638BDBM50321638(1-(3-chloro-5-(4-(3-chloro-4-fluorophenyl)-5-fluor...)
Affinity DataEC50:  480nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321636BDBM50321636(1-(3-chloro-5-(3-(4-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50:  574nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321641BDBM50321641(1-(3-chloro-5-(5-fluoro-4-(4-fluoro-3-(trifluorome...)
Affinity DataEC50:  620nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321639BDBM50321639(1-(5-(4-(3-bromo-4-fluorophenyl)-5-fluorothiazol-2...)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321628BDBM50321628(1-(3-chloro-5-(5-fluoro-4-(2-fluoro-3-(trifluorome...)
Affinity DataEC50:  702nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321637BDBM50321637(1-(3-chloro-5-(1-(2-fluoro-3-(trifluoromethyl)phen...)
Affinity DataEC50: >811nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321635BDBM50321635(1-(3-chloro-5-(5-cyano-4-(4-fluoro-3-(trifluoromet...)
Affinity DataEC50: >898nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321642BDBM50321642(1-(3-chloro-5-(5-fluoro-4-(4-fluoro-3-(2,2,2-trifl...)
Affinity DataEC50:  950nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321643BDBM50321643(1-(3-chloro-5-(4-(3-(ethoxymethyl)-4-fluorophenyl)...)
Affinity DataEC50: >970nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321640BDBM50321640(1-(3-chloro-5-(4-(3,4-dichlorophenyl)-5-fluorothia...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TPO receptor expressed in rat BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed