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Found 19 Enz. Inhib. hit(s) with all data for entry = 50039372
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50324028((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378888(CHEMBL1743603)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50324028((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378888(CHEMBL1743603)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378888(CHEMBL1743603)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50324028((S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dime...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataIC50:  0.810nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50:  13nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataIC50:  450nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50:  3.10E+3nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed