Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50042197
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421905BDBM50421905(CHEMBL553265)
Affinity DataIC50: 0.251nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421907BDBM50421907(CHEMBL540274)
Affinity DataIC50: 0.324nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421906BDBM50421906(CHEMBL544281)
Affinity DataIC50: 1.20nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421895BDBM50421895(CHEMBL555890)
Affinity DataIC50: 1.40nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421903BDBM50421903(CHEMBL545212)
Affinity DataIC50: 1.70nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421913BDBM50421913(CHEMBL545682)
Affinity DataIC50: 1.80nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421899BDBM50421899(CHEMBL545688)
Affinity DataIC50: 1.90nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421926BDBM50421926(CHEMBL541052)
Affinity DataIC50: 2nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421915BDBM50421915(CHEMBL544748)
Affinity DataIC50: 2nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421894BDBM50421894(CHEMBL555581)
Affinity DataIC50: 2.10nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421929BDBM50421929(CHEMBL544987)
Affinity DataIC50: 2.20nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421904BDBM50421904(CHEMBL553561)
Affinity DataIC50: 2.30nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421914BDBM50421914(CHEMBL543810)
Affinity DataIC50: 2.5nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421920BDBM50421920(CHEMBL555401)
Affinity DataIC50: 2.60nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421917BDBM50421917(CHEMBL2093874)
Affinity DataIC50: 3.10nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421912BDBM50421912(CHEMBL545447)
Affinity DataIC50: 3.5nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421900BDBM50421900(CHEMBL545217)
Affinity DataIC50: 4nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421901BDBM50421901(CHEMBL539260)
Affinity DataIC50: 4.30nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421918BDBM50421918(CHEMBL543101)
Affinity DataIC50: 4.60nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421898BDBM50421898(CHEMBL555398)
Affinity DataIC50: 4.70nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421922BDBM50421922(CHEMBL544282)
Affinity DataIC50: 6.30nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421897BDBM50421897(CHEMBL545689)
Affinity DataIC50: 6.60nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421908BDBM50421908(CHEMBL554388)
Affinity DataIC50: 7.10nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155606BDBM50155606(CHEMBL541299 | CHEMBL188713 | 3-Butyl-1,2,3,4,5,6-...)
Affinity DataIC50: 7.60nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421923BDBM50421923(CHEMBL544747)
Affinity DataIC50: 8.70nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421919BDBM50421919(CHEMBL545687)
Affinity DataIC50: 11nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155605BDBM50155605(CHEMBL554988 | CHEMBL186350 | 3-Phenethyl-1,2,3,4,...)
Affinity DataIC50: 17nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421910BDBM50421910(CHEMBL542140)
Affinity DataIC50: 17nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155604BDBM50155604(CHEMBL542390 | CHEMBL185841 | 3-Propyl-1,2,3,4,5,6...)
Affinity DataIC50: 21nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421926BDBM50421926(CHEMBL541052)
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421899BDBM50421899(CHEMBL545688)
Affinity DataIC50: 60nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421900BDBM50421900(CHEMBL545217)
Affinity DataIC50: 62nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50155606BDBM50155606(CHEMBL541299 | CHEMBL188713 | 3-Butyl-1,2,3,4,5,6-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421916BDBM50421916(CHEMBL542387)
Affinity DataIC50: 81nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421924BDBM50421924(CHEMBL544280)
Affinity DataIC50: 98nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421922BDBM50421922(CHEMBL544282)
Affinity DataIC50: 145nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421907BDBM50421907(CHEMBL540274)
Affinity DataIC50: 162nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421894BDBM50421894(CHEMBL555581)
Affinity DataIC50: 166nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421924BDBM50421924(CHEMBL544280)
Affinity DataIC50: 288nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421927BDBM50421927(CHEMBL545448)
Affinity DataIC50: 339nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421909BDBM50421909(CHEMBL2093875)
Affinity DataIC50: 339nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421917BDBM50421917(CHEMBL2093874)
Affinity DataIC50: 389nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421921BDBM50421921(CHEMBL2093876)
Affinity DataIC50: 447nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421912BDBM50421912(CHEMBL545447)
Affinity DataIC50: 589nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421928BDBM50421928(CHEMBL555418)
Affinity DataIC50: 1.18E+3nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421905BDBM50421905(CHEMBL553265)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421896BDBM50421896(CHEMBL539504)
Affinity DataIC50: 3.47E+3nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421904BDBM50421904(CHEMBL553561)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed