Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50044640
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50023412BDBM50023412(CHEMBL3327321)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023416BDBM50023416(CHEMBL3327325)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023414BDBM50023414(CHEMBL3327323)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023417BDBM50023417(CHEMBL3327326)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023416BDBM50023416(CHEMBL3327325)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023389BDBM50023389(CHEMBL3327315)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023412BDBM50023412(CHEMBL3327321)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023413BDBM50023413(CHEMBL3327322)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023414BDBM50023414(CHEMBL3327323)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023403BDBM50023403(CHEMBL3327316)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023417BDBM50023417(CHEMBL3327326)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023413BDBM50023413(CHEMBL3327322)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023407BDBM50023407(CHEMBL3327317)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023403BDBM50023403(CHEMBL3327316)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023389BDBM50023389(CHEMBL3327315)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023419BDBM50023419(CHEMBL3327328)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023419BDBM50023419(CHEMBL3327328)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023407BDBM50023407(CHEMBL3327317)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50023418BDBM50023418(CHEMBL3327327)
Affinity DataIC50: 88nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50023415BDBM50023415(CHEMBL3327324)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023418BDBM50023418(CHEMBL3327327)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023415BDBM50023415(CHEMBL3327324)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023409BDBM50023409(CHEMBL3327318)
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023420BDBM50023420(CHEMBL3327329)
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023420BDBM50023420(CHEMBL3327329)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023410BDBM50023410(CHEMBL3327319)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023409BDBM50023409(CHEMBL3327318)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023411BDBM50023411(CHEMBL3327320)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023410BDBM50023410(CHEMBL3327319)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50023411BDBM50023411(CHEMBL3327320)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed