Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50047877
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of hypotonic solution-induced calcium mobilization by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195055(CHEMBL3954949)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195058(CHEMBL3979286)
Affinity DataIC50: 9.5nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM65888(cid_556143 | 4-(2,4-dimethyl-5-thiazolyl)-N-(2-pyr...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195059(CHEMBL3932523)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195141(CHEMBL3900585)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195142(CHEMBL3925315)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50192802(CHEMBL3927993)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195056(CHEMBL3975583)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195092(CHEMBL3977499)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195220(CHEMBL424708)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195061(CHEMBL3944251)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195139(CHEMBL3946266)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50194946(CHEMBL3900878)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195137(CHEMBL3971104)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50192821(CHEMBL2133556)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50194948(CHEMBL3960032)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195057(CHEMBL3950242)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195221(CHEMBL3971734)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50194949(CHEMBL3898828)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50194947(CHEMBL3970031)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195062(CHEMBL3916322)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195054(CHEMBL1374508)
Affinity DataIC50: 490nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195053(CHEMBL3983567)
Affinity DataIC50: 620nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at rat recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 300 nM 4alphaPDD-induced calcium mobilization by FLIPR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195063(CHEMBL3948261)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195060(CHEMBL3953003)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195140(CHEMBL3923579)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195051(CHEMBL3941505)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195064(CHEMBL3951293)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as blockade of 100 nM capsaicin-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195052(CHEMBL3919377)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50195136(CHEMBL3972736)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed
LigandPNGBDBM50192823(CHEMBL3906074)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2018
Entry Details Article
PubMed