Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50049283
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238182(CHEMBL4100860)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238177(CHEMBL4098072)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238162(CHEMBL4100377)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238182(CHEMBL4100860)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238157(CHEMBL4100777)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238193(CHEMBL4096980)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238172(CHEMBL4079393)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238165(CHEMBL4060003)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238177(CHEMBL4098072)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238181(CHEMBL4071368)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238160(CHEMBL4087268)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238173(CHEMBL4078963)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238185(CHEMBL4094927)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238186(CHEMBL4082362)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238191(CHEMBL4090686)
Affinity DataIC50: 1nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238183(CHEMBL4071012)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238183(CHEMBL4071012)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238174(CHEMBL4098412)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238159(CHEMBL4105526)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238192(CHEMBL4071180)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238168(CHEMBL4081860)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238170(CHEMBL4064942)
Affinity DataIC50: 9nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238176(CHEMBL4091569)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50383274(CHEMBL1229592 | US9670213, WZ4002 | US10167264, WZ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238169(CHEMBL4062543)
Affinity DataIC50: 12nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataKi:  14nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238161(CHEMBL4089601)
Affinity DataIC50: 16nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238156(CHEMBL4089279)
Affinity DataIC50: 16nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238179(CHEMBL4076854)
Affinity DataIC50: 17nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238164(CHEMBL4070707)
Affinity DataIC50: 19nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238158(CHEMBL4102577)
Affinity DataIC50: 22nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238154(CHEMBL321494)
Affinity DataIC50: 24nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238163(CHEMBL4061473)
Affinity DataIC50: 28nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238171(CHEMBL4086878)
Affinity DataIC50: 32nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238184(CHEMBL4102224)
Affinity DataIC50: 33nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238187(CHEMBL4084248)
Affinity DataIC50: 45nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238175(CHEMBL4076363)
Affinity DataIC50: 55nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238188(CHEMBL4082884)
Affinity DataIC50: 57nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238190(CHEMBL4081732)
Affinity DataIC50: 109nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238178(CHEMBL4068092)
Affinity DataIC50: 164nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238155(CHEMBL4067255)
Affinity DataIC50: 183nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238166(CHEMBL4092003)
Affinity DataIC50: 185nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238189(CHEMBL4086078)
Affinity DataIC50: 217nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238167(CHEMBL4062722)
Affinity DataIC50: 265nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50238180(CHEMBL4101193)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human N-terminal GST-fused EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed