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Found
45
Enz. Inhib. hit(s) with all data for entry = 4804
Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM81498
(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
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Affinity Data
Ki: 9.77nM
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Date in BDB:
11/27/2011
Entry Details
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50024206
(3-[2-(dimethylamino)ethyl]indol-5-ol | 5-hydroxy-N...)
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Affinity Data
Ki: 21.4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50001859
(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
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Affinity Data
Ki: 29.5nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM30704
(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
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Affinity Data
Ki: 34.7nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM30707
(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
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Affinity Data
Ki: 39.8nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 46.8nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
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Ki: 70.8nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Affinity Data
Ki: 89.1nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50014945
(alpha-methyl-5-HT | alpha-methyl-5-hydroxytryptami...)
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Affinity Data
Ki: 158nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM30704
(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
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Ki: 245nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM30707
(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
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Affinity Data
Ki: 288nM
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Date in BDB:
11/27/2011
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3D Structure (crystal)
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
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Affinity Data
Ki: 288nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50014945
(alpha-methyl-5-HT | alpha-methyl-5-hydroxytryptami...)
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Affinity Data
Ki: 501nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50001859
(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
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Affinity Data
Ki: 891nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM81498
(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
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Affinity Data
Ki: 912nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50017721
(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
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Affinity Data
Ki: 977nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50024206
(3-[2-(dimethylamino)ethyl]indol-5-ol | 5-hydroxy-N...)
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Affinity Data
Ki: 1.02E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50016900
(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
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Affinity Data
Ki: 1.10E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Affinity Data
Ki: 1.15E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50014407
(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
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Affinity Data
Ki: 1.17E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 1.32E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 1.55E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM82088
(NSC_27400 | CAS_15574-96-6 | PIZOTIFEN)
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Affinity Data
Ki: 2.19E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50014407
(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
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Affinity Data
Ki: 3.39E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 3.55E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50024210
(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
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Ki: 3.72E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 4.17E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Affinity Data
Ki: 4.17E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
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Ki: 4.68E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50017721
(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
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Affinity Data
Ki: 5.25E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM82088
(NSC_27400 | CAS_15574-96-6 | PIZOTIFEN)
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Affinity Data
Ki: 6.17E+3nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM35234
(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
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Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM35234
(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50017696
(N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamin...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50017696
(N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamin...)
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Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM86698
(CHEMBL116590 | CAS_132-17-2 | NSC_2344 | BENZTROPI...)
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Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM86698
(CHEMBL116590 | CAS_132-17-2 | NSC_2344 | BENZTROPI...)
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Affinity Data
Ki: >1.00E+4nM
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In Depth
Date in BDB:
11/27/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50016900
(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
11/27/2011
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Article
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50024210
(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
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Affinity Data
Ki: >1.00E+4nM
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In Depth
Date in BDB:
11/27/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Affinity Data
Ki: >1.00E+4nM
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KEGG
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In Depth
Date in BDB:
11/27/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
DrugBank
KEGG
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PC sid
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In Depth
Date in BDB:
11/27/2011
Entry Details
Article
Copy BDB DOI
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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DrugBank
KEGG
PC cid
PC sid
PDB
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In Depth
Date in BDB:
11/27/2011
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
11/27/2011
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
5-hydroxytryptamine receptor 1A
(Rat)
College of France
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
11/27/2011
Entry Details
Article
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PubMed
Copy reaction URL