Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50041084
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50138701(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)
Affinity DataIC50:  100nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium berghei (strain Anka))
TBA

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  120nMAssay Description:Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404463(CHEMBL339058)
Affinity DataIC50:  300nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium berghei (strain Anka))
TBA

Curated by ChEMBL
LigandPNGBDBM50138701(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)
Affinity DataIC50:  340nMAssay Description:Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium berghei (strain Anka))
TBA

Curated by ChEMBL
LigandPNGBDBM50404463(CHEMBL339058)
Affinity DataIC50:  480nMAssay Description:Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50421660(CHEMBL149353)
Affinity DataIC50:  800nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404479(CHEMBL150543)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium berghei (strain Anka))
TBA

Curated by ChEMBL
LigandPNGBDBM50421660(CHEMBL149353)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for its inhibition against dihydrofolate reductase enzyme of Plasmodium bergheiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404474(CHEMBL357960)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50421665(CHEMBL150248)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50421662(CHEMBL358879)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404475(CHEMBL149408)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium berghei (strain Anka))
TBA

Curated by ChEMBL
LigandPNGBDBM50404477(CHEMBL150538)
Affinity DataIC50:  2.00E+4nMAssay Description:Tested for the inhibition of Plasmodium berghei dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50421664(CHEMBL150683)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50421664(CHEMBL150683)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50421665(CHEMBL150248)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50421663(CHEMBL150863)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50421663(CHEMBL150863)
Affinity DataIC50: >4.50E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404478(CHEMBL439995)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50404473(CHEMBL150700)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50421662(CHEMBL358879)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50138701(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50404477(CHEMBL150538)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404477(CHEMBL150538)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50404473(CHEMBL150700)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50404475(CHEMBL149408)
Affinity DataIC50: >9.00E+5nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50404479(CHEMBL150543)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition against dihydrofolate reductase enzyme of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50421661(CHEMBL150017)
Affinity DataIC50:  4.50E+6nMAssay Description:Inhibition against dihydrofolate reductase enzyme of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed