Compile Data Set for Download or QSAR
Report error Found 167 Enz. Inhib. hit(s) with all data for entry = 50048638
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081909(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4-diamine | 5-...)
Affinity DataKi:  295nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081909(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4-diamine | 5-...)
Affinity DataKi:  295nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081905(5-(3-Butoxy-benzyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataKi:  331nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081905(5-(3-Butoxy-benzyl)-pyrimidine-2,4-diamine | CHEMB...)
Affinity DataKi:  331nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081917(5-(3-Hexyloxy-benzyl)-pyrimidine-2,4-diamine | CHE...)
Affinity DataKi:  407nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081917(5-(3-Hexyloxy-benzyl)-pyrimidine-2,4-diamine | CHE...)
Affinity DataKi:  407nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405977(CHEMBL277391)
Affinity DataKi:  537nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405977(CHEMBL277391)
Affinity DataKi:  537nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405996(CHEMBL29712)
Affinity DataKi:  708nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405996(CHEMBL29712)
Affinity DataKi:  708nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405992(CHEMBL281760)
Affinity DataKi:  1.38E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405992(CHEMBL281760)
Affinity DataKi:  1.38E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405993(CHEMBL19113)
Affinity DataKi:  1.48E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405993(CHEMBL19113)
Affinity DataKi:  1.48E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405968(CHEMBL18898)
Affinity DataKi:  1.55E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405968(CHEMBL18898)
Affinity DataKi:  1.55E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405973(CHEMBL417095)
Affinity DataKi:  1.59E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405973(CHEMBL417095)
Affinity DataKi:  1.59E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081910(5-(3-Octyloxy-benzyl)-pyrimidine-2,4-diamine | CHE...)
Affinity DataKi:  1.66E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)
Affinity DataKi:  1.66E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)
Affinity DataKi:  1.66E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM77567(cid_623352 | SMR000427733 | MLS001049199 | 5-(4-Bu...)
Affinity DataKi:  1.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM77567(cid_623352 | SMR000427733 | MLS001049199 | 5-(4-Bu...)
Affinity DataKi:  1.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405960(CHEMBL19406)
Affinity DataKi:  1.95E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405960(CHEMBL19406)
Affinity DataKi:  1.95E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50081917(5-(3-Hexyloxy-benzyl)-pyrimidine-2,4-diamine | CHE...)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405962(CHEMBL19772)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405962(CHEMBL19772)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50081917(5-(3-Hexyloxy-benzyl)-pyrimidine-2,4-diamine | CHE...)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50138691(Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...)
Affinity DataKi:  2.19E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50138691(Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...)
Affinity DataKi:  2.19E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50081909(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4-diamine | 5-...)
Affinity DataKi:  2.34E+3nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50081909(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4-diamine | 5-...)
Affinity DataKi:  2.34E+3nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081908(5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...)
Affinity DataKi:  2.46E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081908(5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...)
Affinity DataKi:  2.46E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405975(CHEMBL280884)
Affinity DataKi:  2.51E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405975(CHEMBL280884)
Affinity DataKi:  2.51E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405955(CHEMBL31351)
Affinity DataKi:  2.63E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405955(CHEMBL31351)
Affinity DataKi:  2.63E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405984(CHEMBL434787)
Affinity DataKi:  2.63E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405984(CHEMBL434787)
Affinity DataKi:  2.63E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081914(5-(3-Heptyloxy-benzyl)-pyrimidine-2,4-diamine | CH...)
Affinity DataKi:  2.69E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50081914(5-(3-Heptyloxy-benzyl)-pyrimidine-2,4-diamine | CH...)
Affinity DataKi:  2.69E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405959(CHEMBL31912)
Affinity DataKi:  2.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405959(CHEMBL31912)
Affinity DataKi:  2.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver Dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  2.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50406002(CHEMBL18912)
Affinity DataKi:  2.82E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50405970(CHEMBL19780)
Affinity DataKi:  3.09E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
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