Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50004876
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029526([(S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029533((2-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-h...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029521(({3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hex...)
Affinity DataKi:  5.5nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029517(((S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataKi:  6.90nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029538(3-(Cyclopropyl-phenyl-methyl)-4-hydroxy-11-propyl-...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029523([(R)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029520(3-(Cyclopropyl-phenyl-methyl)-2,5,6,7,8,9,10,11-oc...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029543((3-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-h...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029529(10-Cyclopropylmethyl-3-(cyclopropyl-phenyl-methyl)...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029545(11-Cyclopropylmethyl-3-(cyclopropyl-phenyl-methyl)...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029542(3-(Cyclopropyl-phenyl-methyl)-4-hydroxy-10-(2-meth...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029518(3-(Cyclopropyl-phenyl-methyl)-4-hydroxy-11-isobuty...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029546(11-Butyl-3-(cyclopropyl-phenyl-methyl)-4-hydroxy-6...)
Affinity DataKi:  31nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029519(((R)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029536(3-(Cyclopropyl-phenyl-methyl)-11-ethyl-4-hydroxy-6...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029516(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataKi:  33nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029530(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataKi:  42nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029525((S)-2-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,1...)
Affinity DataKi:  43nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029531(3-(Cyclopropyl-phenyl-methyl)-4-hydroxy-11-(3-meth...)
Affinity DataKi:  50nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029528(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataKi:  55nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029532(3-Dicyclopropylmethyl-4-hydroxy-6,7,8,9,10,11-hexa...)
Affinity DataKi:  57nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029522(4-Hydroxy-3-(1-phenyl-propyl)-6,7,8,9,10,11-hexahy...)
Affinity DataKi:  58nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029524(1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataKi:  72nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM771(CHEMBL16584 | 3-[cyclopropyl(phenyl)methyl]-4-hydr...)
Affinity DataKi:  96nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029535(3-(Cyclopropyl-phenyl-methyl)-4-hydroxy-11-(tetrah...)
Affinity DataKi:  120nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029544(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataKi:  240nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029539(11-Benzyl-3-dicyclopropylmethyl-4-hydroxy-6,7,8,9,...)
Affinity DataKi:  260nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029527(11-Benzyl-4-hydroxy-3-(1-phenyl-propyl)-6,7,8,9,10...)
Affinity DataKi:  266nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029537(4-Hydroxy-11-methyl-3-(1-phenyl-propyl)-6,7,8,9,10...)
Affinity DataKi:  330nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029534(1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataKi:  450nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029541((E)-N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,1...)
Affinity DataKi:  470nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029538(3-(Cyclopropyl-phenyl-methyl)-4-hydroxy-11-propyl-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029541((E)-N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,1...)
Affinity DataIC50: 1.71E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029516(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataIC50: 1.73E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029534(1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataIC50: 2.17E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029528(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataIC50: 2.19E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029530(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataIC50: 2.35E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029525((S)-2-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,1...)
Affinity DataIC50: 2.92E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029521(({3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hex...)
Affinity DataIC50: 2.98E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029517(((S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataIC50: 3.18E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029533((2-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-h...)
Affinity DataIC50: 3.34E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029544(N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataIC50: 3.51E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029526([(S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataIC50: 4.53E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029543((3-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-h...)
Affinity DataIC50: 4.95E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029520(3-(Cyclopropyl-phenyl-methyl)-2,5,6,7,8,9,10,11-oc...)
Affinity DataIC50: 5.73E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029524(1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-he...)
Affinity DataIC50: 6.00E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029519(((R)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed