Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50004880
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50:  42nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against dihydro folate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against dihydro folate reductase from human recombinant sourcesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against dihydro folate reductase from human recombinant sourcesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50: >6.90E+4nMAssay Description:Inhibitory activity against dihydro folate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50: >6.90E+4nMAssay Description:Inhibitory activity against dihydro folate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029548(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,4a,7,7...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed