Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50004960
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030567(6,6'-Dibromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dio...)
Affinity DataIC50: 48nMAssay Description:IC50 value was measured as DNA dependent DNA polymerase associated activity by using 0.05 units of radiolabeled template poly(rA)-oligo(dT).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50: 56nMAssay Description:IC50 value was measured as DNA dependent DNA polymerase associated activity by using 0.05 units of radiolabeled template poly(rA)-oligo(dT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030567(6,6'-Dibromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dio...)
Affinity DataIC50: 1.90E+3nMAssay Description:IC50 value was measured as RNA dependent DNA polymerase associated activity by using 10e-3 units of radiolabeled template poly(rA)-oligo(dT).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:IC50 value was measured as RNA dependent DNA polymerase associated activity by using 1*10e-3 units of radiolabeled template poly(rC)-oligo(dG)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50: 4.50E+3nMAssay Description:IC50 value was measured as RNA dependent DNA polymerase associated activity by using 1*10e-3 units of radiolabeled template poly(rA)-oligo(dT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030567(6,6'-Dibromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dio...)
Affinity DataIC50: 1.10E+4nMAssay Description:IC50 value was measured as RNA dependent DNA polymerase associated activity by using 10e-3 units of radiolabeled template poly(rC)-oligo(dG).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed