Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50004961
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50000041((+/-)(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030575(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030573(7-Methyl-8-oxo-5-phenyl-7,8-dihydro-[1,7]naphthyri...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030576(4-(4-Fluoro-phenyl)-2-methyl-1-oxo-1,2-dihydro-iso...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030584(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030581(2-Methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030572(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030607(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030611(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030574(7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyr...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030591(6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoqu...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030569(1-(2-Chloro-benzyl)-1-methyl-3-(2,6,7-trimethyl-1-...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030582(7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyr...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030585(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030594(2,6,7-Trimethyl-1-oxo-4-phenyl-1,2-dihydro-isoquin...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030604(3-[(2-Methoxy-benzylamino)-methyl]-2,6,7-trimethyl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030583(1-Benzyl-1-methyl-3-(2,6,7-trimethyl-1-oxo-4-pheny...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030571(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030579(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030593(N-Methyl-N-(2-methyl-1-oxo-4-phenyl-1,2-dihydro-is...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030598(1-(2-Methoxy-benzyl)-1-methyl-3-(2,6,7-trimethyl-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030587(3-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-meth...)
Affinity DataIC50: 23nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030608(1-(3,5-Dimethyl-benzyl)-1-methyl-3-(2,6,7-trimethy...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030588(2-Methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030606(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030597(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030601(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 34nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030578(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 34nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030577(1-(3,5-Bis-trifluoromethyl-benzyl)-1-methyl-3-(2,6...)
Affinity DataIC50: 54nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030580(1-Benzyl-1-ethyl-3-(2,6,7-trimethyl-1-oxo-4-phenyl...)
Affinity DataIC50: 66nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030605(N-(3,5-Bis-trifluoromethyl-benzyl)-N-methyl-2-(2-m...)
Affinity DataIC50: 68nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030600(1-Benzyl-1-methyl-3-(2-methyl-1-oxo-4-phenyl-1,2-d...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030610(2-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-N-(2-m...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030592(1-Benzyl-3-(2,6,7-trimethyl-1-oxo-4-phenyl-1,2-dih...)
Affinity DataIC50: 140nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030609(3-[(3,5-Bis-trifluoromethyl-benzylamino)-methyl]-2...)
Affinity DataIC50: 250nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030586(3-[(2-Methoxy-benzylamino)-methyl]-2-methyl-4-phen...)
Affinity DataIC50: 460nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030595(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 470nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030568(1-(2-Chloro-benzyl)-3-[4-(4-fluoro-phenyl)-2-methy...)
Affinity DataIC50: 480nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030596(3-{[(3,5-Bis-trifluoromethyl-benzyl)-methyl-amino]...)
Affinity DataIC50: 600nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030602(3-{[(2-Methoxy-benzyl)-methyl-amino]-methyl}-2,6,7...)
Affinity DataIC50: 800nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030599(1-m-Tolyl-3-(2,6,7-trimethyl-1-oxo-4-phenyl-1,2-di...)
Affinity DataIC50: 840nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030603(2-Methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3...)
Affinity DataIC50: 860nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030590(1-Benzyl-3-[4-(4-fluoro-phenyl)-2-methyl-1-oxo-1,2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030570(1-Methyl-1-phenethyl-3-(2,6,7-trimethyl-1-oxo-4-ph...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed