Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50004963
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030630(AIDA | AIDC | 1-Amino-indan-1,5-dicarboxylic acid(...)
Affinity DataIC50: 7.00E+3nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inositol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030628(CHEMBL444589 | 4-(Amino-carboxy-methyl)-2-hydroxy-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inositol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030628(CHEMBL444589 | 4-(Amino-carboxy-methyl)-2-hydroxy-...)
Affinity DataIC50: 4.80E+4nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030629(4-(Amino-carboxy-methyl)-benzoic acid | (S)-4CPG |...)
Affinity DataIC50: 6.50E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inositol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030627(CHEMBL299683 | MCPG | (R,S)-alpha-Methyl-4-carboxy...)
Affinity DataIC50: 1.55E+5nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inositol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030627(CHEMBL299683 | MCPG | (R,S)-alpha-Methyl-4-carboxy...)
Affinity DataIC50: 3.40E+5nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030629(4-(Amino-carboxy-methyl)-benzoic acid | (S)-4CPG |...)
Affinity DataIC50: 5.77E+5nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030629(4-(Amino-carboxy-methyl)-benzoic acid | (S)-4CPG |...)
Affinity DataIC50: 1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030627(CHEMBL299683 | MCPG | (R,S)-alpha-Methyl-4-carboxy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50030628(CHEMBL444589 | 4-(Amino-carboxy-methyl)-2-hydroxy-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed