Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 494
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3148BDBM3148(5-ethyl-3-{[(2-methoxy-5,6-dimethylpyridin-3-yl)me...)
Affinity DataIC50: 9nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3142BDBM3142(5-ethyl-3-{[(2-methoxy-5-methylphenyl)methyl]amino...)
Affinity DataIC50: 23nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3141BDBM3141(5-ethyl-3-{[(2-methoxy-4-methylphenyl)methyl]amino...)
Affinity DataIC50: 32nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3145BDBM3145(5-ethyl-3-{[(5-ethyl-2-methoxyphenyl)methyl]amino}...)
Affinity DataIC50: 32nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3146BDBM3146(5-ethyl-3-{[(5-ethyl-2-methoxy-4-methylphenyl)meth...)
Affinity DataIC50: 33nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3147BDBM3147(5-ethyl-3-{[(6-methoxy-2,3-dihydro-1H-inden-5-yl)m...)
Affinity DataIC50: 40nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3121BDBM3121(5-ethyl-3-{[(2-methoxyphenyl)methyl]amino}-6-methy...)
Affinity DataIC50: 265nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3123BDBM3123(3-{[(2-ethoxyphenyl)methyl]amino}-5-ethyl-6-methyl...)
Affinity DataIC50: 350nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3144BDBM3144(5-ethyl-3-{[(4-ethyl-2-methoxyphenyl)methyl]amino}...)
Affinity DataIC50: 510nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3124BDBM3124(5-ethyl-6-methyl-3-{[(2-nitrophenyl)methyl]amino}-...)
Affinity DataIC50: 530nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3119BDBM3119(5-ethyl-3-{[(2-methoxypyridin-3-yl)methyl]amino}-6...)
Affinity DataIC50: 680nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3125BDBM3125(2-{[(5-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-y...)
Affinity DataIC50: 790nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3135BDBM3135(5-ethyl-3-{[(3-methoxyphenyl)methyl]amino}-6-methy...)
Affinity DataIC50: 1.25E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3143BDBM3143(5-ethyl-3-{[(2-methoxy-6-methylphenyl)methyl]amino...)
Affinity DataIC50: 1.30E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3126BDBM3126(5-ethyl-3-{[(2-fluorophenyl)methyl]amino}-6-methyl...)
Affinity DataIC50: 1.40E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3127BDBM3127(3-{[(2-chlorophenyl)methyl]amino}-5-ethyl-6-methyl...)
Affinity DataIC50: 1.45E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3128BDBM3128(5-ethyl-6-methyl-3-({[2-(methylsulfanyl)phenyl]met...)
Affinity DataIC50: 1.50E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3139BDBM3139(5-ethyl-3-{[(3-methoxypyridin-2-yl)methyl]amino}-6...)
Affinity DataIC50: 1.55E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3129BDBM3129(5-ethyl-6-methyl-3-{[(2-methylphenyl)methyl]amino}...)
Affinity DataIC50: 2.20E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3140BDBM3140(5-ethyl-3-{[(2-methoxy-3-methylphenyl)methyl]amino...)
Affinity DataIC50: 3.80E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3130BDBM3130(5-ethyl-3-{[(2-hydroxyphenyl)methyl]amino}-6-methy...)
Affinity DataIC50: 4.60E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1298BDBM1298(CHEMBL86064 | 2-pyridinone deriv. 28 | 3-(benzylam...)
Affinity DataIC50: 5.30E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3131BDBM3131(5-ethyl-3-{[(2-ethylphenyl)methyl]amino}-6-methyl-...)
Affinity DataIC50: 6.90E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3136BDBM3136(5-ethyl-3-{[(4-methoxyphenyl)methyl]amino}-6-methy...)
Affinity DataIC50: 7.50E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3138BDBM3138(5-ethyl-3-{[(4-methoxypyridin-3-yl)methyl]amino}-6...)
Affinity DataIC50: 1.00E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3132BDBM3132(5-ethyl-6-methyl-3-({[2-(trifluoromethyl)phenyl]me...)
Affinity DataIC50: 1.25E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3133BDBM3133(3-{[(2-aminophenyl)methyl]amino}-5-ethyl-6-methyl-...)
Affinity DataIC50: 2.80E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3134BDBM3134(5-ethyl-3-({[2-(methoxymethyl)phenyl]methyl}amino)...)
Affinity DataIC50: 3.55E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 3137BDBM3137(5-ethyl-3-{[(3-methoxypyridin-4-yl)methyl]amino}-6...)
Affinity DataIC50: 1.10E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 1308BDBM1308(5-ethyl-6-methyl-3-[(pyridin-3-ylmethyl)amino]-1,2...)
Affinity DataIC50: 3.00E+5nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed