Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50005187
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033969BDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50: 10nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033969BDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50: 10nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033960BDBM50033960(N-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 11nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033949BDBM50033949(1-[5-(4,5-Dicyclohexyl-1H-imidazol-2-ylsulfanyl)-p...)
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033950BDBM50033950(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diisopropyl-1H-i...)
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033971BDBM50033971(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033966BDBM50033966(N-[5-[(1H,9H-dibenzo[4,5:8,9] [1,3]dioxonino[6,7-d...)
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033975BDBM50033975(1-{5-[4,5-Bis-(3-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033997BDBM50033997(1-{5-[4,5-Bis-(4-fluoro-phenyl)-1H-imidazol-2-ylsu...)
Affinity DataIC50: 40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033998BDBM50033998(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50: 40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033955BDBM50033955(N-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033952BDBM50033952(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033957BDBM50033957(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50: 50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033974BDBM50033974(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-dipropyl-1H-imid...)
Affinity DataIC50: 60nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033995BDBM50033995(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(1H-8-oxa-1,...)
Affinity DataIC50: 60nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033984BDBM50033984(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-thiophen-2-yl...)
Affinity DataIC50: 60nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033967BDBM50033967(1-(2-Butoxy-ethyl)-3-(2,4-difluoro-phenyl)-1-[5-(4...)
Affinity DataIC50: 70nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033953BDBM50033953(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50: 70nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033978BDBM50033978(1-{5-[4,5-Bis-(4-methylsulfanyl-phenyl)-1H-imidazo...)
Affinity DataIC50: 70nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033980BDBM50033980(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033964BDBM50033964(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-p-tolyl-1H-im...)
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033990BDBM50033990(3-(2,4-Difluoro-phenyl)-1-{2-[2-(4,5-diphenyl-1H-i...)
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033954BDBM50033954(1-(2-Diethylamino-ethyl)-3-(2,4-difluoro-phenyl)-1...)
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033980BDBM50033980(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033948BDBM50033948(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50: 90nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033982BDBM50033982({5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol-2...)
Affinity DataIC50: 120nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033968BDBM50033968(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 140nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033981BDBM50033981(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 160nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033951BDBM50033951(3-(2,4-Difluoro-phenyl)-1-(2-{[2-(4,5-diphenyl-1H-...)
Affinity DataIC50: 170nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033977BDBM50033977(1-{2-[2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-et...)
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033959BDBM50033959(1-(2-Butoxy-ethyl)-1-[5-(4,5-diphenyl-1H-imidazol-...)
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033956BDBM50033956(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-furan-2-yl-1H...)
Affinity DataIC50: 200nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033979BDBM50033979(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 230nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033991BDBM50033991(3-(2,4-Difluoro-phenyl)-1-(2-{[2-(4,5-diphenyl-1H-...)
Affinity DataIC50: 240nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033994BDBM50033994(1-(2-{[2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-e...)
Affinity DataIC50: 260nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033983BDBM50033983(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 270nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033976BDBM50033976(1-{5-[4,5-Bis-(4-methylsulfanyl-phenyl)-1H-imidazo...)
Affinity DataIC50: 280nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033962BDBM50033962(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 340nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033961BDBM50033961(1-{5-[4,5-Bis-(2-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 350nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033970BDBM50033970(1-(2-{[2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-e...)
Affinity DataIC50: 350nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033965BDBM50033965(1-(2-{3-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50: 480nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033972BDBM50033972(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 500nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033985BDBM50033985({5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsul...)
Affinity DataIC50: 640nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033987BDBM50033987(1-(2-Diethylamino-ethyl)-1-[5-(4,5-diphenyl-1H-imi...)
Affinity DataIC50: 660nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033986BDBM50033986(1-(2-{2-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50: 850nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033992BDBM50033992(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-pyridin-2-yl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033958BDBM50033958(1-(2-{2-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033988BDBM50033988(1-(2-{2-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033996BDBM50033996(1-{5-[4,5-Bis-(4-hydroxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 2.40E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033973BDBM50033973(1-{5-[4,5-Bis-(4-trifluoromethyl-phenyl)-1H-imidaz...)
Affinity DataIC50: 3.99E+4nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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