Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 1727
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337378(US9745317, 16 | 5-{4-[(3-Hydroxy-2,3-dihydrofuro[3...)
Affinity DataKi:  4.80nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337370(US9745317, 9 | US9745317, 10 | 5-[4-(2,3-dihydro-1...)
Affinity DataKi:  8.40nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337374(US9745317, 12 | 6-[4-(2,3-Dihydro-1H-pyrrolo[3,2-c...)
Affinity DataKi:  11.1nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337368(US9745317, 6 | (+)-5-[4-(2,3-dihydrofuro[3,2-c]pyr...)
Affinity DataKi:  12.6nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337369(US9745317, 7 | (−)-5-[4-(2,3-dihydrofuro[3,2...)
Affinity DataKi:  12.7nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337366(US9745317, 4 | 5-[4-(2,3-Dihydro-1H-pyrrolo[3,2-c]...)
Affinity DataKi:  14nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337367(US9745317, 5 | 5-[4-(2,3-dihydrofuro[3,2-c]pyridin...)
Affinity DataKi:  14nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337377(US9745317, 15 | 4,6-Dimethyl-5-[2-methyl-4-(1,2,3,...)
Affinity DataKi:  18.1nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337379(US9745317, 17 | 4-[4-(4,6-Dimethylpyrimidin-5-yl)-...)
Affinity DataKi:  28.9nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337370(US9745317, 9 | US9745317, 10 | 5-[4-(2,3-dihydro-1...)
Affinity DataKi:  35.6nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337389(US9745317, 27)
Affinity DataKi:  44.4nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337375(US9745317, 13 | 6-[4-(2,3-Dihydrofuro[3,2-c]pyridi...)
Affinity DataKi:  46.1nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337370(US9745317, 9 | US9745317, 10 | 5-[4-(2,3-dihydro-1...)
Affinity DataKi:  50.5nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337365(US9745317, 3 | 5-[4-(2,3-Dihydrofuro[3,2-c]pyridin...)
Affinity DataKi:  52nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337380(US9745317, 18)
Affinity DataKi:  52.1nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337373(US9745317, 11 | 5-[4-(6, 7-Dihydro-5H-pyrrolo[2, 3...)
Affinity DataKi:  60.4nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337376(US9745317, 14 | 5-[4-(3,4-Dihydro-2H-pyrano[3,2-c]...)
Affinity DataKi:  70.3nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337386(US9745317, 25 | US9745317, 24)
Affinity DataKi:  75.8nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337363(US9745317, 1 | 4-[4-(4,6-Dimethylpyrimidin-5-yl)-3...)
Affinity DataKi:  76.8nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337364(US9745317, 2 | 4-[4-(4,6-Dimethylpyrimidin-5-yl)-3...)
Affinity DataKi:  78.1nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337383(US9745317, 22 | US9745317, 23 | US9745317, 21)
Affinity DataKi:  82.5nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337381(US9745317, 19)
Affinity DataKi:  156nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337388(US9745317, 26)
Affinity DataKi:  162nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337386(US9745317, 25 | US9745317, 24)
Affinity DataKi:  201nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337383(US9745317, 22 | US9745317, 23 | US9745317, 21)
Affinity DataKi:  202nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337390(US9745317, 28)
Affinity DataKi:  202nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337382(US9745317, 20)
Affinity DataKi:  446nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337383(US9745317, 22 | US9745317, 23 | US9745317, 21)
Affinity DataKi:  706nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent