Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50004113
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...)
Affinity DataIC50: 2.86E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50222303(6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM23446(3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop...)
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed