Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50005435
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036920(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 0.0210nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036920(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 0.0210nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036918(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 0.190nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036928(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 0.400nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036925(3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 0.590nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036919(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 0.640nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036917(3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 1.70nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036926(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 1.80nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036930(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 2.60nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036923(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 3.40nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036927(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 4.10nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036923(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036927(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 5.20nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036919(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 5.80nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036922(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 7nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036929(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036920(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036920(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036928(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 11nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036925(3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 17nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036931(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 23nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036917(3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 27nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036929(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 32nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036931(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 33nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 40nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036922(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 43nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036918(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 49nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036926(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 94nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036921(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 120nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036930(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 220nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 290nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036924(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 350nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036924(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 500nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036921(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 600nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 7.00E+3nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed