Compile Data Set for Download or QSAR
Report error Found 126 Enz. Inhib. hit(s) with all data for entry = 50036260
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039315BDBM50039315((1S,9aR,11aS)-5,9a,11a-Trimethyl-1-(3-methyl-butyr...)
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039259BDBM50039259((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.120nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039294BDBM50039294((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.160nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043604BDBM50043604(17-tert-Butylcarbamoyl-10,13-dimethyl-2,7,8,9,10,1...)
Affinity DataIC50: 0.180nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334788BDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 0.180nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039288BDBM50039288((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039295BDBM50039295(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.230nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039320BDBM50039320((4aR,6aS,7S)-1,4a,6a-Trimethyl-2-oxo-hexadecahydro...)
Affinity DataIC50: 0.230nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039318BDBM50039318((1S,9aR,11aS)-1-Butyryl-9a,11a-dimethyl-1,2,3,3a,3...)
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039278BDBM50039278((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039273BDBM50039273((1S,9aR,11aS)-6-Bromo-9a,11a-dimethyl-1-(3-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368883BDBM50368883(CHEMBL1159458)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039302BDBM50039302(9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039312BDBM50039312((1S,9aR,11aS)-5,6,9a,11a-Tetramethyl-7-oxo-2,3,3a,...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039282BDBM50039282((1S,9aR,11aS)-9a,11a-Dimethyl-1-(2,4,6-triisopropy...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039296BDBM50039296((1S,9aR,11aS)-9a,11a-Dimethyl-1-(piperidine-1-carb...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039275BDBM50039275((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.600nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039285BDBM50039285((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 0.880nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039276BDBM50039276((1S,9aR,11aS)-9a,11a-Dimethyl-1-nonanoyl-1,2,3,3a,...)
Affinity DataKi:  1nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039277BDBM50039277((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataKi:  1.10nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039284BDBM50039284(9a,11a-Dimethyl-1-(thiomorpholine-4-carbonyl)-1,2,...)
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039305BDBM50039305((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-5-propyl-2,3,3...)
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039304BDBM50039304((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039308BDBM50039308((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 1.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039261BDBM50039261((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039256BDBM50039256((1S,9aR,11aS)-6-Bromo-5,9a,11a-trimethyl-7-oxo-2,3...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039283BDBM50039283((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039263BDBM50039263((10S,13S,17S)-10,13-Dimethyl-3-oxo-1,2,3,6,7,8,9,1...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039291BDBM50039291((1S,9aR,11aS)-6-Chloro-9a,11a-dimethyl-7-oxo-2,3,3...)
Affinity DataIC50: 1.90nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039306BDBM50039306((1S,9aR,11aS)-6-Bromo-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039271BDBM50039271((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039287BDBM50039287((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039315BDBM50039315((1S,9aR,11aS)-5,9a,11a-Trimethyl-1-(3-methyl-butyr...)
Affinity DataKi:  3.10nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039273BDBM50039273((1S,9aR,11aS)-6-Bromo-9a,11a-dimethyl-1-(3-methyl-...)
Affinity DataKi:  3.20nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039266BDBM50039266((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039270BDBM50039270((1S,9aR,11aS)-8,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 3.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039322BDBM50039322((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-2,3,3a,3b,4,5,...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039264BDBM50039264((1S,9aR,11aS)-5-Ethyl-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039316BDBM50039316((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataKi:  3.60nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039267BDBM50039267((1S,10aR,12aS)-10a,12a-Dimethyl-8-oxo-1,2,3,3a,3b,...)
Affinity DataIC50: 3.80nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039323BDBM50039323((1S,9aR,11aS)-6,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 3.90nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039299BDBM50039299((1S,9aR,11aS)-1-(2-Cyclohexyl-acetyl)-9a,11a-dimet...)
Affinity DataKi:  4nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039279BDBM50039279((1S,9aR,11aS)-9a,11a-Dimethyl-7-oxo-5-propyl-2,3,3...)
Affinity DataIC50: 4.20nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039269BDBM50039269((10S,13S,17S)-10,13-Dimethyl-3-oxo-1,2,3,6,7,8,9,1...)
Affinity DataIC50: 4.40nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039319BDBM50039319((1S,9aR,11aS)-5,6,9a,11a-Tetramethyl-7-oxo-2,3,3a,...)
Affinity DataIC50: 4.5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039324BDBM50039324((1S,9aR,11aS)-6-Bromo-9a,11a-dimethyl-7-oxo-2,3,3a...)
Affinity DataKi:  4.5nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039310BDBM50039310((1S,9aR,11aS)-5-Isopropyl-9a,11a-dimethyl-7-oxo-2,...)
Affinity DataIC50: 4.90nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039307BDBM50039307((10S,13S,17S)-6,10,13-Trimethyl-3-oxo-1,2,3,6,7,8,...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039320BDBM50039320((4aR,6aS,7S)-1,4a,6a-Trimethyl-2-oxo-hexadecahydro...)
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50039258BDBM50039258((1S,9aR,11aS)-5,9a,11a-Trimethyl-7-oxo-2,3,3a,3b,4...)
Affinity DataIC50: 5.70nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
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