Compile Data Set for Download or QSAR
Report error Found 97 Enz. Inhib. hit(s) with all data for entry = 2577
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372270(8-(3-azabicyclo[3.1.0] hexan-3-yl)-3,4- dimethylpy...)
Affinity DataEC50:  21nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372260(2-[4-[[(3,4-Dimethylpyrimido[4',5':4,5]thieno[2,3-...)
Affinity DataEC50:  23nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372267(3,4-dimethyl-N-(1-(5- (trifluoromethyl) pyrimidin-...)
Affinity DataEC50:  30nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372270(8-(3-azabicyclo[3.1.0] hexan-3-yl)-3,4- dimethylpy...)
Affinity DataEC50:  36nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372266(3,4-dimethyl-8-(pyrrolidin-1- yl)pyrimido[4',5':4,...)
Affinity DataEC50:  48nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372260(2-[4-[[(3,4-Dimethylpyrimido[4',5':4,5]thieno[2,3-...)
Affinity DataEC50:  52nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372297(US10239887, Cpd. No. 35 | 1-(3-((3,4- dimethylpyri...)
Affinity DataEC50:  53nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372300(US10239887, Cpd. No. 38 | 8-chloro-N-cyclopropyl- ...)
Affinity DataEC50:  56.5nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372286(3,4-dimethyl-8-(3- (pyridin-4-yl)azetidin- 1-yl)py...)
Affinity DataEC50:  64nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372266(3,4-dimethyl-8-(pyrrolidin-1- yl)pyrimido[4',5':4,...)
Affinity DataEC50:  75nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372265(N-cyclobutyl-3,4- dimethylpyrimido[4',5':4,5] thie...)
Affinity DataEC50:  83nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372302(US10239887, Cpd. No. 40 | 8-chloro-N-(2,2- dimethy...)
Affinity DataEC50:  109nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372301(US10239887, Cpd. No. 39 | 2-[4-[[(8-chloro-7,9- di...)
Affinity DataEC50:  110nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372265(N-cyclobutyl-3,4- dimethylpyrimido[4',5':4,5] thie...)
Affinity DataEC50:  112nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372264(3,4-dimethyl-8-(piperidin-1- yl)pyrimido[4',5':4,5...)
Affinity DataEC50:  120nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372273(6-(3,4-dimethylpyrimido [4',5':4,5]thieno[2,3-c] p...)
Affinity DataEC50:  123nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372275(8-methyl-4- (pyrrolidin-1-yl) pyrido[3',2':4,5]thi...)
Affinity DataEC50:  161nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372286(3,4-dimethyl-8-(3- (pyridin-4-yl)azetidin- 1-yl)py...)
Affinity DataEC50:  185nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372264(3,4-dimethyl-8-(piperidin-1- yl)pyrimido[4',5':4,5...)
Affinity DataEC50:  215nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372273(6-(3,4-dimethylpyrimido [4',5':4,5]thieno[2,3-c] p...)
Affinity DataEC50:  231nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372267(3,4-dimethyl-N-(1-(5- (trifluoromethyl) pyrimidin-...)
Affinity DataEC50:  251nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372271(1-(3,4- dimethylpyrimido [4',5':4,5]thieno[2,3-c] ...)
Affinity DataEC50:  257nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372304(US10239887, Cpd. No. 42 | 4-(azetidin-1-yl)-8- chl...)
Affinity DataEC50:  269nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372326(US10239887, Cpd. No. 63 | N-[1-(5-Fluoropyrimidin-...)
Affinity DataEC50:  284nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372303(US10239887, Cpd. No. 41 | 8-chloro-N- (2-ethylcycl...)
Affinity DataEC50:  324nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372271(1-(3,4- dimethylpyrimido [4',5':4,5]thieno[2,3-c] ...)
Affinity DataEC50:  326nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372269(8-(azetidin-1-yl)-3,4- dimethylpyrimido [4',5':4,5...)
Affinity DataEC50:  351nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372307(US10239887, Cpd. No. 45 | 8-chloro-7,9-dimethyl-N-...)
Affinity DataEC50:  358nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372316(US10239887, Cpd. No. 53 | 8-chloro-N-(3- methoxypr...)
Affinity DataEC50:  365nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372276(4-(3,3-difluoropyrrolidin- 1-yl)-8-methylpyrido [3...)
Affinity DataEC50:  377nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372269(8-(azetidin-1-yl)-3,4- dimethylpyrimido [4',5':4,5...)
Affinity DataEC50:  405nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372299(US10239887, Cpd. No. 37 | 8-chloro-N-(3,3-difluoro...)
Affinity DataEC50:  406nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372274(8-(3-(methoxymethyl) azetidin-1-yl)-3,4- dimethylp...)
Affinity DataEC50:  418nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372278(8-methyl-N-(1-(5- (trifluoromethyl) pyrimidin-2-yl...)
Affinity DataEC50:  424nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372282(8-(3,3-difluoroazetidin- 1-yl)-3,4-dimethylpyrimid...)
Affinity DataEC50:  426nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372263(3,4-dimethyl-N-(tetrahydro- 2H-pyran-4-yl) pyrimid...)
Affinity DataEC50:  446nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372280(6-(8-methylpyrido [3',2':4,5]thieno[3,2-d] pyrimid...)
Affinity DataEC50:  456nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372287(N-cyclopropyl- 3,4-dimethylpyrimido [4',5':4,5]thi...)
Affinity DataEC50:  468nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372263(3,4-dimethyl-N-(tetrahydro- 2H-pyran-4-yl) pyrimid...)
Affinity DataEC50:  521nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372313(US10239887, Cpd. No. 50 | 8-chloro-N-cyclopentyl-7...)
Affinity DataEC50:  593nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372309(US10239887, Cpd. No. 46 | 8-chloro-N-isobutyl- 7,9...)
Affinity DataEC50:  601nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372268(8-(4- cyclopropylpiperazin- 1-yl)-3,4-dimethylpyri...)
Affinity DataEC50:  616nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372261(N,N,3,4-tetramethylpyrimido[4',5':4,5]thieno[2,3-c...)
Affinity DataEC50:  638nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372296(US10239887, Cpd. No. 34 | 1-(3,4-dimethylpyrimido ...)
Affinity DataEC50:  660nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372278(8-methyl-N-(1-(5- (trifluoromethyl) pyrimidin-2-yl...)
Affinity DataEC50:  674nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372312(US10239887, Cpd. No. 49 | 8-chloro-N-cyclobutyl- 7...)
Affinity DataEC50:  695nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372268(8-(4- cyclopropylpiperazin- 1-yl)-3,4-dimethylpyri...)
Affinity DataEC50:  700nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372262(N-cyclohexyl-3,4- dimethylpyrimido[4',5':4,5] thie...)
Affinity DataEC50:  724nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM372261(N,N,3,4-tetramethylpyrimido[4',5':4,5]thieno[2,3-c...)
Affinity DataEC50:  724nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372279(4-(azetidin-1-yl)-8- methylpyrido[3',2':4,5] thien...)
Affinity DataEC50:  807nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

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